C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: endothelin 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000337938 EDN3-001 ENSG00000124205 9606 + 20:59300427-59325992 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastLungOvaryPlacentaENST00000337938
Transcript ID Brain Breast Lung Ovary Placenta
ENST00000337938 0.755±0.00 0.502±0.15 0.035±0.00 0.171±0.00 0.159±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00093L CIL_00093L_0001 VISTA 20:59111478-59715059
CIL_00074T CIL_00074T_0001 CGP 20:59191020-59325992

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001755 IEA neural crest cell migration
GO:0002690 IDA positive regulation of leukocyte chemotaxis
GO:0003100 IDA regulation of systemic arterial blood pressure by endothelin
GO:0005102 TAS receptor binding
GO:0005179 IDA hormone activity
GO:0005576 TAS:IEA extracellular region
GO:0005615 IDA extracellular space
GO:0006874 IEA cellular calcium ion homeostasis
GO:0007165 TAS signal transduction
GO:0007166 IDA cell surface receptor signaling pathway
GO:0007267 TAS cell-cell signaling
GO:0007275 TAS multicellular organismal development
GO:0008015 TAS blood circulation
GO:0008284 IEA positive regulation of cell proliferation
GO:0010460 IDA positive regulation of heart rate
GO:0010961 IEA cellular magnesium ion homeostasis
GO:0014826 IDA vein smooth muscle contraction
GO:0019229 IEA regulation of vasoconstriction
GO:0030072 IDA peptide hormone secretion
GO:0030182 IEA neuron differentiation
GO:0030318 IEA melanocyte differentiation
GO:0030334 IEA regulation of cell migration
GO:0030593 IDA neutrophil chemotaxis
GO:0042310 IDA vasoconstriction
GO:0043406 IDA positive regulation of MAP kinase activity
GO:0045840 IDA positive regulation of mitosis
GO:0046887 IDA positive regulation of hormone secretion
GO:0048016 IDA inositol phosphate-mediated signaling
GO:0048070 IEA regulation of developmental pigmentation
GO:1901381 IEA positive regulation of potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000029030 Edn3-001 protein_coding Mus_musculus 0 562
ENSMUST00000137369 Edn3-003 retained_intron Mus_musculus 0 268
ENSMUST00000140908 Edn3-002 protein_coding Mus_musculus 0 226
ENSMUST00000162473 Edn3-004 processed_transcript Mus_musculus 6e-19 100

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