C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: major histocompatibility complex, class II, DQ alpha 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000343139 HLA-DQA1-001 ENSG00000196735 9606 + 6:32637357-32643652 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000343139
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000343139 2.969±0.00 9.832±0.00 1.115±0.00 0.505±0.39 5.076±1.60 1.208±0.94 1.561±0.79 2.945±1.18 0.572±0.00 45.296±27.78 2.644±0.00 2.431±1.90 10.654±4.99 2.300±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002XS CIL_0002XS_0008 CGP 6:32552990-32647062
CIL_0001PL CIL_0001PL_0006 CGP 6:32628179-32668383

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0005515 IEA protein binding
GO:0005764 IEA lysosome
GO:0005765 TAS lysosomal membrane
GO:0005768 IEA endosome
GO:0005886 TAS plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0006955 NAS:IEA immune response
GO:0009897 IEA external side of plasma membrane
GO:0012507 TAS ER to Golgi transport vesicle membrane
GO:0016020 IDA:IEA membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019882 IEA antigen processing and presentation
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030658 TAS transport vesicle membrane
GO:0030666 TAS endocytic vesicle membrane
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0031295 TAS T cell costimulation
GO:0032395 TAS MHC class II receptor activity
GO:0032588 TAS trans-Golgi network membrane
GO:0034341 IEA response to interferon-gamma
GO:0042605 ISS peptide antigen binding
GO:0042613 ISS:IEA MHC class II protein complex
GO:0045582 IEA positive regulation of T cell differentiation
GO:0048002 IEA antigen processing and presentation of peptide antigen
GO:0050852 TAS T cell receptor signaling pathway
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0071556 TAS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000040655 H2-Aa-001 protein_coding Mus_musculus 0 608
ENSMUST00000174751 H2-Aa-004 protein_coding Mus_musculus 0 460

Loading