C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: chemokine (C-X-C motif) ligand 12
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000343575 CXCL12-001 ENSG00000107562 9606 - 10:44377133-44385092 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000343575
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000343575 160.803±0.00 225.838±0.00 13.460±0.00 1.914±0.29 40.739±29.13 44.649±36.60 17.322±12.77 27.963±10.48 23.480±3.61 17.804±10.19 9.059±4.87 38.762±33.99 3.201±0.73 20.885±15.45

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007QA CIL_0007QA_0001 VISTA 10:43961287-44562544

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005102 TAS receptor binding
GO:0005576 TAS:IEA extracellular region
GO:0006874 TAS cellular calcium ion homeostasis
GO:0006935 TAS chemotaxis
GO:0006955 IEA immune response
GO:0007155 TAS cell adhesion
GO:0007165 TAS signal transduction
GO:0007186 TAS G-protein coupled receptor signaling pathway
GO:0008009 TAS:IEA chemokine activity
GO:0008015 TAS blood circulation
GO:0008064 TAS regulation of actin polymerization or depolymerization
GO:0008083 IEA growth factor activity
GO:0009615 TAS response to virus
GO:0042379 IMP chemokine receptor binding
GO:0045236 IDA CXCR chemokine receptor binding
GO:0045785 IDA positive regulation of cell adhesion
GO:0060326 IDA cell chemotaxis
GO:0070062 IDA extracellular vesicular exosome
GO:0070098 IDA chemokine-mediated signaling pathway
GO:0090026 IDA positive regulation of monocyte chemotaxis
GO:0090280 TAS positive regulation of calcium ion import
GO:1902230 IDA negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1903237 IDA negative regulation of leukocyte tethering or rolling
GO:2000107 IDA negative regulation of leukocyte apoptotic process
GO:2000406 IDA positive regulation of T cell migration

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000134244 Cxcl12-004 retained_intron Mus_musculus 0 521
ENSMUST00000112866 Cxcl12-001 protein_coding Mus_musculus 0 521
ENSMUST00000073043 Cxcl12-003 protein_coding Mus_musculus 0 372
ENSMUST00000112871 Cxcl12-002 protein_coding Mus_musculus 0 372

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