C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: forkhead box O3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000343882 FOXO3-001 ENSG00000118689 9606 + 6:108559835-108684774 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000343882
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000343882 12.795±0.00 1.866±0.00 9.585±4.92 7.668±2.91 2.963±2.31 5.964±4.79 5.795±3.51 3.598±0.69 11.118±6.06 14.902±8.56 5.492±2.47 2.081±0.79 6.016±3.94

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008YH CIL_0008YH_0001 VISTA 6:108288605-108890079
CIL_0001OT CIL_0001OT_0002 CGP 6:108294894-108684774

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0001047 ISS core promoter binding
GO:0003677 IDA DNA binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 ISS regulation of transcription from RNA polymerase II promoter
GO:0006417 IDA regulation of translation
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0019901 IPI protein kinase binding
GO:0031490 ISS chromatin DNA binding
GO:0034599 ISS cellular response to oxidative stress
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0043525 IMP positive regulation of neuron apoptotic process
GO:0043565 IDA:IEA sequence-specific DNA binding
GO:0045087 TAS innate immune response
GO:0045648 IDA positive regulation of erythrocyte differentiation
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000105502 Foxo3-001 protein_coding Mus_musculus 0 3369
ENSMUST00000056974 Foxo3-002 protein_coding Mus_musculus 0 3249
ENSMUST00000175881 Foxo3-004 protein_coding Mus_musculus 0 2809
ENSMUST00000105501 Foxo3-003 protein_coding Mus_musculus 0 889
ENSMUST00000177542 Foxo3-005 protein_coding Mus_musculus 0 440
ENSMUST00000053764 Foxo1-001 protein_coding Mus_musculus 0 278

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