C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutathione peroxidase 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000354171 GPX4-002 ENSG00000167468 9606 + 19:1103937-1106790 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartTestisENST00000354171
Transcript ID Heart Testis
ENST00000354171 3.662±0.00 145.321±110.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000QU CIL_0000QU_0001 CGP 19:1086579-1106791
CIL_0000QT CIL_0000QT_0001 CGP 19:1103926-1174283

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004602 TAS:IEA glutathione peroxidase activity
GO:0005634 IDA nucleus
GO:0005739 TAS mitochondrion
GO:0005829 TAS cytosol
GO:0006644 TAS phospholipid metabolic process
GO:0006749 IEA glutathione metabolic process
GO:0006979 IEA response to oxidative stress
GO:0007275 IEA multicellular organismal development
GO:0007568 IEA aging
GO:0008430 IEA selenium binding
GO:0019369 TAS arachidonic acid metabolic process
GO:0019372 TAS lipoxygenase pathway
GO:0032355 IEA response to estradiol
GO:0042744 IEA hydrogen peroxide catabolic process
GO:0043295 IEA glutathione binding
GO:0044281 TAS small molecule metabolic process
GO:0047066 IEA phospholipid-hydroperoxide glutathione peroxidase activity
GO:0050727 IEA regulation of inflammatory response
GO:0055114 TAS:IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000105372 Gpx4-001 protein_coding Mus_musculus 0 828
ENSMUST00000097227 Gpx4-002 protein_coding Mus_musculus 0 702
ENSMUST00000183037 Gpx4-007 protein_coding Mus_musculus 0 678
ENSMUST00000145703 Gpx4-003 processed_transcript Mus_musculus 0 422

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