C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: F-box and leucine-rich repeat protein 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000355619 FBXL3-001 ENSG00000005812 9606 - 13:77005254-77027150 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000355619
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000355619 15.484±0.00 15.273±0.00 2.016±0.00 9.390±4.21 8.463±4.41 8.184±3.65 4.028±1.82 7.500±5.43 4.615±0.37 8.511±0.59 4.176±3.30 7.396±3.57 7.312±1.32 15.794±6.28

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00004A CIL_00004A_0001 CGP 13:76948497-77002517
CIL_0004PQ CIL_0004PQ_0002 CGP 13:76990660-77027195
CIL_00004B CIL_00004B_0001 CGP 13:76992598-77327050

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000151 NAS ubiquitin ligase complex
GO:0004842 NAS ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 ISS nucleus
GO:0005829 ISS cytosol
GO:0016567 ISS protein ubiquitination
GO:0019005 IDA SCF ubiquitin ligase complex
GO:0031146 IDA SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031648 ISS protein destabilization
GO:0042752 IMP regulation of circadian rhythm
GO:0043153 ISS entrainment of circadian clock by photoperiod
GO:0043161 IEA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0048511 IEA rhythmic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000022720 Fbxl3-001 protein_coding Mus_musculus 0 2180
ENSMUST00000145693 Fbxl3-002 protein_coding Mus_musculus 0 1962
ENSMUST00000132004 Fbxl3-003 protein_coding Mus_musculus 0 1572
ENSMUST00000127113 Fbxl3-006 retained_intron Mus_musculus 0 723
ENSMUST00000144141 Fbxl3-004 protein_coding Mus_musculus 0 643
ENSMUST00000123043 Fbxl3-005 protein_coding Mus_musculus 0 206

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