C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Rho/Rac guanine nucleotide exchange factor (GEF) 18
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000359920 ARHGEF18-001 ENSG00000104880 9606 + 19:7439688-7472477 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004YI CIL_0004YI_0001 CGP 19:7348943-7472477
CIL_0002U4 CIL_0002U4_0001 CGP 19:7395113-7497449

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005085 IDA guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0007264 IDA small GTPase mediated signal transduction
GO:0008360 IDA regulation of cell shape
GO:0030036 IDA actin cytoskeleton organization
GO:0030054 TAS cell junction
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0043065 TAS positive regulation of apoptotic process
GO:0043547 IDA positive regulation of GTPase activity
GO:0045177 IDA apical part of cell
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000004684 Arhgef18-001 protein_coding Mus_musculus 0 2159
ENSMUST00000131773 Arhgef18-002 retained_intron Mus_musculus 0 1550
ENSMUST00000156085 Arhgef18-003 retained_intron Mus_musculus 0 1480
ENSMUST00000145360 Arhgef18-006 retained_intron Mus_musculus 0 368

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