C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: complement component 1, s subcomponent
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000360817 C1S-004 ENSG00000182326 9606 + 12:7060676-7070943 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000360817
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000360817 70.895±0.00 3.452±0.00 1.572±0.00 43.012±0.00 31.325±15.13 18.987±14.43 145.094±125.47 101.086±71.53 36.490±21.17 8.668±2.74 43.953±28.03 24.367±0.00 20.230±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00001H CIL_00001H_0001 CGP 12:6988259-7092607

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004252 IEA:IDA serine-type endopeptidase activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0006508 IEA proteolysis
GO:0006956 TAS complement activation
GO:0006958 TAS complement activation, classical pathway
GO:0042802 IPI identical protein binding
GO:0045087 TAS innate immune response
GO:0070062 IDA extracellular vesicular exosome
GO:0072562 IDA blood microparticle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000068797 C1s2-001 protein_coding Mus_musculus 0 1602
ENSMUST00000162443 C1s1-002 protein_coding Mus_musculus 0 1567
ENSMUST00000160505 C1s1-001 protein_coding Mus_musculus 0 1567
ENSMUST00000159463 C1s1-004 protein_coding Mus_musculus 0 390

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