C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ATPase, Na+/K+ transporting, alpha 2 polypeptide
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000361216 ATP1A2-001 ENSG00000018625 9606 + 1:160115773-160143591 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000361216
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000361216 7.956±0.00 3.337±0.00 103.195±55.19 6.109±4.01 10.693±8.03 29.357±23.30 0.853±0.82 5.048±0.00 89.664±0.00 2.121±1.67 1.448±0.84 7.472±6.43

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005I6 CIL_0005I6_0001 CGP 1:160091340-160143591

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001504 IEA neurotransmitter uptake
GO:0002026 IEA regulation of the force of heart contraction
GO:0002087 IEA regulation of respiratory gaseous exchange by neurological system process
GO:0005391 IDA:IEA sodium:potassium-exchanging ATPase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0005886 IDA plasma membrane
GO:0005890 IDA sodium:potassium-exchanging ATPase complex
GO:0005901 IEA caveola
GO:0006754 IEA ATP biosynthetic process
GO:0006813 NAS:IEA potassium ion transport
GO:0006814 NAS:IEA sodium ion transport
GO:0006883 IDA cellular sodium ion homeostasis
GO:0006937 IEA regulation of muscle contraction
GO:0006940 IEA regulation of smooth muscle contraction
GO:0006942 NAS regulation of striated muscle contraction
GO:0008217 IEA regulation of blood pressure
GO:0008344 IEA adult locomotory behavior
GO:0008542 IEA visual learning
GO:0010107 IDA potassium ion import
GO:0010881 TAS regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0015991 IEA ATP hydrolysis coupled proton transport
GO:0016021 IEA integral component of membrane
GO:0019229 IEA regulation of vasoconstriction
GO:0030007 IDA cellular potassium ion homeostasis
GO:0030315 IEA T-tubule
GO:0031982 IDA vesicle
GO:0034220 TAS ion transmembrane transport
GO:0035094 IEA response to nicotine
GO:0036376 IDA sodium ion export from cell
GO:0040011 IEA locomotion
GO:0042383 IEA sarcolemma
GO:0043005 IEA neuron projection
GO:0043197 IEA dendritic spine
GO:0045202 IEA synapse
GO:0045822 IEA negative regulation of heart contraction
GO:0045988 IEA negative regulation of striated muscle contraction
GO:0046872 IEA metal ion binding
GO:0051087 IPI chaperone binding
GO:0051481 IEA negative regulation of cytosolic calcium ion concentration
GO:0055085 TAS transmembrane transport
GO:0055119 TAS relaxation of cardiac muscle
GO:0060048 TAS cardiac muscle contraction
GO:0071260 IEA cellular response to mechanical stimulus
GO:0071383 IDA cellular response to steroid hormone stimulus
GO:0086004 IEA regulation of cardiac muscle cell contraction
GO:0086012 TAS membrane depolarization during cardiac muscle cell action potential
GO:0086064 TAS cell communication by electrical coupling involved in cardiac conduction
GO:1903416 IC response to glycoside
GO:1990239 IDA steroid hormone binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000085913 Atp1a2-001 protein_coding Mus_musculus 0 4148
ENSMUST00000097464 Atp1a2-004 protein_coding Mus_musculus 0 3832
ENSMUST00000131751 Atp1a2-003 retained_intron Mus_musculus 0 3476
ENSMUST00000080882 Atp1a3-001 protein_coding Mus_musculus 0 2529
ENSMUST00000102858 Atp1a3-002 protein_coding Mus_musculus 0 2501
ENSMUST00000137679 Atp1a2-002 protein_coding Mus_musculus 0 2490
ENSDART00000104950 atp1a3a-001 protein_coding Danio_rerio 0 2041
ENSMUST00000111243 Atp1a4-001 protein_coding Mus_musculus 0 1879
ENSMUST00000146595 Atp1a3-003 retained_intron Mus_musculus 0 1133
ENSMUST00000139528 Igsf8-004 protein_coding Mus_musculus 0 195
ENSMUST00000155363 Igsf8-005 retained_intron Mus_musculus 0 195

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