C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: histone deacetylase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000368632 HDAC2-003 ENSG00000196591 9606 - 6:113940718-113971157 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000368632
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000368632 18.694±0.00 15.354±0.00 1.780±0.00 6.184±0.75 7.601±2.56 14.908±0.00 7.167±5.86 14.410±0.00 4.721±1.15 7.739±6.60 14.214±0.00 15.121±7.41 20.241±0.88 27.571±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007P5 CIL_0007P5_0009 UCNEbase 6:113887002-114451190

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IDA nuclear chromatin
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001103 IPI RNA polymerase II repressing transcription factor binding
GO:0003682 ISS chromatin binding
GO:0004407 IEA:IDA histone deacetylase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 TAS cytoplasm
GO:0006338 IC chromatin remodeling
GO:0006344 IMP maintenance of chromatin silencing
GO:0006351 IEA transcription, DNA-templated
GO:0007596 TAS blood coagulation
GO:0008134 IPI transcription factor binding
GO:0008284 IMP positive regulation of cell proliferation
GO:0009913 ISS epidermal cell differentiation
GO:0010870 IMP positive regulation of receptor biosynthetic process
GO:0010977 ISS negative regulation of neuron projection development
GO:0016358 ISS dendrite development
GO:0016575 IMP:IEA histone deacetylation
GO:0016580 IDA Sin3 complex
GO:0016581 IDA NuRD complex
GO:0019213 ISS deacetylase activity
GO:0019899 IPI enzyme binding
GO:0031492 IDA nucleosomal DNA binding
GO:0032041 IEA NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0032922 ISS circadian regulation of gene expression
GO:0032967 IC positive regulation of collagen biosynthetic process
GO:0033558 IMP protein deacetylase activity
GO:0035098 IDA ESC/E(Z) complex
GO:0042475 ISS odontogenesis of dentin-containing tooth
GO:0042733 ISS embryonic digit morphogenesis
GO:0043044 IDA ATP-dependent chromatin remodeling
GO:0043066 ISS negative regulation of apoptotic process
GO:0043234 IDA protein complex
GO:0043433 IMP negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043565 IDA sequence-specific DNA binding
GO:0044822 IDA poly(A) RNA binding
GO:0045347 IC negative regulation of MHC class II biosynthetic process
GO:0045786 TAS negative regulation of cell cycle
GO:0045862 IMP positive regulation of proteolysis
GO:0045892 IC negative regulation of transcription, DNA-templated
GO:0045893 IC positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0046969 IEA NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970 IEA NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0060789 ISS hair follicle placode formation
GO:0061029 ISS eyelid development in camera-type eye
GO:0061198 ISS fungiform papilla formation
GO:0070932 ISS histone H3 deacetylation
GO:0070933 ISS histone H4 deacetylation
GO:0097372 IEA NAD-dependent histone deacetylase activity (H3-K18 specific)

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000019911 Hdac2-001 protein_coding Mus_musculus 0 2289
ENSMUST00000105510 Hdac2-002 protein_coding Mus_musculus 0 1074
ENSMUST00000128031 Hdac2-003 processed_transcript Mus_musculus 0 556

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