C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: suppressor of fused homolog (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000369902 SUFU-001 ENSG00000107882 9606 + 10:102503987-102633535 protein_coding

Homo sapiens EnsemblGRCh38

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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000369902
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000369902 3.764±0.00 3.266±0.00 2.014±0.00 2.615±1.62 1.812±1.56 2.238±0.00 2.943±2.15 1.505±0.54 1.638±1.38 3.394±2.70 4.715±2.80 7.868±2.26 8.872±0.72

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008MQ CIL_0008MQ_0001 VISTA 10:102469546-103070739
CIL_0005WM CIL_0005WM_0001 CGP 10:102479229-102633535
CIL_00065X CIL_00065X_0001 CGP 10:102503987-102658407

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001501 TAS skeletal system development
GO:0001843 IEA neural tube closure
GO:0001947 IEA heart looping
GO:0003714 TAS transcription corepressor activity
GO:0004871 TAS signal transducer activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005929 IEA cilium
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0006508 TAS proteolysis
GO:0007165 TAS signal transduction
GO:0007275 TAS multicellular organismal development
GO:0007368 IEA determination of left/right symmetry
GO:0008013 IEA beta-catenin binding
GO:0008134 IDA:IEA transcription factor binding
GO:0019901 IPI protein kinase binding
GO:0021513 IEA spinal cord dorsal/ventral patterning
GO:0021775 IEA smoothened signaling pathway involved in ventral spinal cord interneuron specification
GO:0021776 IEA smoothened signaling pathway involved in spinal cord motor neuron cell fate specification
GO:0042992 TAS negative regulation of transcription factor import into nucleus
GO:0042994 IEA cytoplasmic sequestering of transcription factor
GO:0043433 TAS negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043588 IEA skin development
GO:0045668 TAS negative regulation of osteoblast differentiation
GO:0045879 TAS negative regulation of smoothened signaling pathway
GO:0072372 IEA primary cilium
GO:1901621 IEA negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
GO:2000059 IEA negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000039922 Sufu-001 protein_coding Mus_musculus 0 2183
ENSMUST00000111867 Sufu-002 protein_coding Mus_musculus 0 2148
ENSMUST00000118440 Sufu-004 protein_coding Mus_musculus 0 1796
ENSMUST00000120778 Sufu-003 protein_coding Mus_musculus 0 957
ENSMUST00000123252 Sufu-006 processed_transcript Mus_musculus 0 307
ENSMUST00000144341 Sufu-005 retained_intron Mus_musculus 0 243

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