C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: myosin VI
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000369977 MYO6-002 ENSG00000196586 9606 + 6:75749332-75916612 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastKidneyLungMuscleOvaryPlacentaTestisENST00000369977
Transcript ID Brain Breast Kidney Lung Muscle Ovary Placenta Testis
ENST00000369977 2.745±0.00 1.053±0.00 3.390±2.63 1.064±0.19 0.092±0.00 0.609±0.00 0.712±0.25 1.304±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006PS CIL_0006PS_0001 CGP 6:75601509-75919537
CIL_0006PV CIL_0006PV_0001 CGP 6:75749192-76072678

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001726 IDA ruffle
GO:0003774 ISS:IEA motor activity
GO:0003779 TAS actin binding
GO:0005515 IPI protein binding
GO:0005516 ISS calmodulin binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005737 ISS cytoplasm
GO:0005765 TAS lysosomal membrane
GO:0005794 IDA Golgi apparatus
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0005902 IEA microvillus
GO:0005905 IEA coated pit
GO:0005938 ISS cell cortex
GO:0006605 IEA protein targeting
GO:0006886 ISS intracellular protein transport
GO:0006897 ISS endocytosis
GO:0007268 TAS synaptic transmission
GO:0007416 IEA synapse assembly
GO:0007605 IEA sensory perception of sound
GO:0007626 IEA locomotory behavior
GO:0008152 IEA metabolic process
GO:0012506 IEA vesicle membrane
GO:0014047 IEA glutamate secretion
GO:0016020 IDA membrane
GO:0016023 IDA cytoplasmic membrane-bounded vesicle
GO:0016358 IEA dendrite development
GO:0016459 IEA myosin complex
GO:0016461 TAS unconventional myosin complex
GO:0016591 IDA DNA-directed RNA polymerase II, holoenzyme
GO:0030048 ISS actin filament-based movement
GO:0030139 ISS endocytic vesicle
GO:0030330 IDA DNA damage response, signal transduction by p53 class mediator
GO:0030424 IEA axon
GO:0031941 IDA filamentous actin
GO:0031965 IDA nuclear membrane
GO:0032587 IEA ruffle membrane
GO:0042472 IEA inner ear morphogenesis
GO:0042491 IEA auditory receptor cell differentiation
GO:0042493 IEA response to drug
GO:0043025 IEA neuronal cell body
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043234 IEA protein complex
GO:0043531 ISS ADP binding
GO:0045177 IEA apical part of cell
GO:0045334 IDA clathrin-coated endocytic vesicle
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048167 IEA regulation of synaptic plasticity
GO:0048471 ISS perinuclear region of cytoplasm
GO:0048839 IEA inner ear development
GO:0051015 ISS actin filament binding
GO:0051046 IMP regulation of secretion
GO:0060001 NAS minus-end directed microfilament motor activity
GO:0061024 TAS membrane organization
GO:0070062 IDA extracellular vesicular exosome
GO:0071257 IEA cellular response to electrical stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000127779 Myo6-014 protein_coding Mus_musculus 0 4721
ENSMUST00000113268 Myo6-002 protein_coding Mus_musculus 0 4623
ENSMUST00000076140 Myo6-003 protein_coding Mus_musculus 0 4337
ENSMUST00000035889 Myo6-001 protein_coding Mus_musculus 0 3742
ENSMUST00000184480 Myo6-012 protein_coding Mus_musculus 0 3740
ENSMUST00000113266 Myo6-004 protein_coding Mus_musculus 0 3733
ENSMUST00000156199 Myo6-006 retained_intron Mus_musculus 0 281

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