C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: endothelin 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000371028 EDN3-201 ENSG00000124205 9606 + 20:59300444-59325991 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartMuscleOvaryPlacentaTestisENST00000371028
Transcript ID Brain Breast Colon Heart Muscle Ovary Placenta Testis
ENST00000371028 0.401±0.00 0.089±0.00 2.357±0.00 0.013±0.00 0.513±0.00 0.125±0.00 0.439±0.46 0.506±0.20

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00093L CIL_00093L_0001 VISTA 20:59111478-59715059
CIL_00074T CIL_00074T_0001 CGP 20:59191020-59325992

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002690 IDA positive regulation of leukocyte chemotaxis
GO:0003100 IDA regulation of systemic arterial blood pressure by endothelin
GO:0005102 TAS receptor binding
GO:0005179 IDA hormone activity
GO:0005576 TAS:IEA extracellular region
GO:0005615 IDA extracellular space
GO:0007165 TAS signal transduction
GO:0007166 IDA cell surface receptor signaling pathway
GO:0007267 TAS cell-cell signaling
GO:0007275 TAS multicellular organismal development
GO:0008015 TAS blood circulation
GO:0010460 IDA positive regulation of heart rate
GO:0014826 IDA vein smooth muscle contraction
GO:0019229 IEA regulation of vasoconstriction
GO:0030072 IDA peptide hormone secretion
GO:0030593 IDA neutrophil chemotaxis
GO:0042310 IDA vasoconstriction
GO:0043406 IDA positive regulation of MAP kinase activity
GO:0045840 IDA positive regulation of mitosis
GO:0046887 IDA positive regulation of hormone secretion
GO:0048016 IDA inositol phosphate-mediated signaling

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000029030 Edn3-001 protein_coding Mus_musculus 0 562
ENSMUST00000137369 Edn3-003 retained_intron Mus_musculus 0 268
ENSMUST00000140908 Edn3-002 protein_coding Mus_musculus 0 226
ENSMUST00000162473 Edn3-004 processed_transcript Mus_musculus 5e-19 100

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