C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: major histocompatibility complex, class II, DQ alpha 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000374949 HLA-DQA1-009 ENSG00000196735 9606 + 6:32637420-32643017 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalColonKidneyLiverTestisENST00000374949
Transcript ID Adrenal Colon Kidney Liver Testis
ENST00000374949 16.196±0.00 0.262±0.00 2.677±0.00 0.304±0.00 1.049±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002XS CIL_0002XS_0008 CGP 6:32552990-32647062
CIL_0001PL CIL_0001PL_0006 CGP 6:32628179-32668383

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0005515 IEA protein binding
GO:0005765 TAS lysosomal membrane
GO:0005768 IEA endosome
GO:0005886 TAS plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0006955 NAS:IEA immune response
GO:0012507 TAS ER to Golgi transport vesicle membrane
GO:0016020 IDA:IEA membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019882 IEA antigen processing and presentation
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030658 TAS transport vesicle membrane
GO:0030666 TAS endocytic vesicle membrane
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0031295 TAS T cell costimulation
GO:0032395 TAS MHC class II receptor activity
GO:0032588 TAS trans-Golgi network membrane
GO:0042605 ISS peptide antigen binding
GO:0042613 ISS:IEA MHC class II protein complex
GO:0050852 TAS T cell receptor signaling pathway
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0071556 TAS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000040655 H2-Aa-001 protein_coding Mus_musculus 0 608
ENSMUST00000174751 H2-Aa-004 protein_coding Mus_musculus 0 460

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