C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: calcium/calmodulin-dependent serine protein kinase (MAGUK family)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000378158 CASK-001 ENSG00000147044 9606 - X:41519653-41923339 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; OvaryTestisENST00000378158
Transcript ID Ovary Testis
ENST00000378158 1.297±0.00 0.362±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007LW CIL_0007LW_0001 UCNEbase X:41232520-41520330
CIL_0001X6 CIL_0001X6_0002 CGP X:41447434-41923463
CIL_0001JA CIL_0001JA_0002 CGP X:41514934-41923463

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001953 IMP negative regulation of cell-matrix adhesion
GO:0004385 TAS guanylate kinase activity
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005604 IDA basement membrane
GO:0005652 IDA nuclear lamina
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005886 TAS plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005925 IDA focal adhesion
GO:0006468 IEA protein phosphorylation
GO:0007155 TAS cell adhesion
GO:0010839 IMP negative regulation of keratinocyte proliferation
GO:0015629 TAS actin cytoskeleton
GO:0016363 IDA nuclear matrix
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030198 TAS extracellular matrix organization
GO:0042734 ISS presynaptic membrane
GO:0046939 TAS nucleotide phosphorylation
GO:0060170 ISS ciliary membrane
GO:0061045 IMP negative regulation of wound healing
GO:0090288 IMP negative regulation of cellular response to growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000033321 Cask-002 protein_coding Mus_musculus 0 5590
ENSMUST00000115438 Cask-001 protein_coding Mus_musculus 0 3186
ENSMUST00000115436 Cask-201 protein_coding Mus_musculus 0 3070
ENSMUST00000152358 Cask-010 retained_intron Mus_musculus 0 3070
ENSMUST00000156096 Cask-003 protein_coding Mus_musculus 0 2494
ENSMUST00000128012 Cask-011 protein_coding Mus_musculus 0 1149
ENSMUST00000115435 Cask-005 protein_coding Mus_musculus 0 1035
ENSMUST00000139735 Cask-008 protein_coding Mus_musculus 0 996
ENSMUST00000124710 Cask-006 protein_coding Mus_musculus 0 689
ENSMUST00000128095 Cask-004 protein_coding Mus_musculus 0 558
ENSMUST00000132240 Cask-009 processed_transcript Mus_musculus 0 274

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