C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: calcium/calmodulin-dependent serine protein kinase (MAGUK family)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000115438 Cask-001 ENSMUSG00000031012 10090 - X:13517080-13846578 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000115438
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000115438 0.810±0.18 0.879±0.16 0.687±0.00 2.992±0.91 0.689±0.30 2.153±0.00 0.184±0.03 0.537±0.23 0.257±0.06 0.488±0.00 0.221±0.09 0.946±0.36 0.118±0.05 0.033±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007LW CIL_0007LW_0002 UCNEbase X:13169486-13522078
CIL_0001X6 CIL_0001X6_0003 CGP X:13466110-13851367
CIL_0001JA CIL_0001JA_0003 CGP X:13517080-13851367

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001953 IEA negative regulation of cell-matrix adhesion
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005604 IDA basement membrane
GO:0005634 IDA nucleus
GO:0005652 IEA nuclear lamina
GO:0005730 IEA nucleolus
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0005911 IDA cell-cell junction
GO:0005925 IEA focal adhesion
GO:0006468 IEA protein phosphorylation
GO:0010839 IEA negative regulation of keratinocyte proliferation
GO:0016020 IDA membrane
GO:0016323 IDA basolateral plasma membrane
GO:0016363 IEA nuclear matrix
GO:0042043 IDA neurexin family protein binding
GO:0045202 IDA synapse
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0061045 IEA negative regulation of wound healing
GO:0070509 IMP calcium ion import
GO:0090280 IDA positive regulation of calcium ion import
GO:0090288 IEA negative regulation of cellular response to growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000100849 caska-202 protein_coding Danio_rerio 0 2228
ENSDART00000144150 caska-001 protein_coding Danio_rerio 0 2200
ENSDART00000040843 caska-201 protein_coding Danio_rerio 0 2167
ENST00000378154 CASK-006 protein_coding Homo_sapiens 0 3238
ENST00000378158 CASK-001 protein_coding Homo_sapiens 0 3186
ENST00000378163 CASK-007 protein_coding Homo_sapiens 0 6505
ENST00000378166 CASK-005 protein_coding Homo_sapiens 0 4765
ENST00000378168 CASK-012 protein_coding Homo_sapiens 0 2645
ENST00000378179 CASK-002 protein_coding Homo_sapiens 0 2747
ENST00000421587 CASK-004 protein_coding Homo_sapiens 0 3434
ENST00000442742 CASK-013 protein_coding Homo_sapiens 0 2651
ENST00000468986 CASK-008 processed_transcript Homo_sapiens 0 643
ENST00000469265 CASK-011 processed_transcript Homo_sapiens 0 577
ENST00000472704 CASK-003 processed_transcript Homo_sapiens 0 532
ENST00000477823 CASK-009 processed_transcript Homo_sapiens 0 459
ENST00000486402 CASK-010 processed_transcript Homo_sapiens 0 483

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