C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: RAD50 homolog (S. cerevisiae)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000378823 RAD50-001 ENSG00000113522 9606 + 5:132556938-132646344 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000378823
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000378823 1.686±0.00 1.522±0.00 1.065±0.00 1.849±1.00 1.278±0.00 1.708±0.67 1.549±1.33 1.067±0.28 1.586±0.14 0.879±0.13 1.570±1.38 2.064±1.04 1.623±0.53 3.594±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00093D CIL_00093D_0001 VISTA 5:131965137-132566411
CIL_0007RF CIL_0007RF_0001 VISTA 5:131967147-132570227

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000014 IDA single-stranded DNA endodeoxyribonuclease activity
GO:0000019 IDA regulation of mitotic recombination
GO:0000723 TAS:IEA telomere maintenance
GO:0000724 TAS double-strand break repair via homologous recombination
GO:0000737 IDA DNA catabolic process, endonucleolytic
GO:0000784 IDA nuclear chromosome, telomeric region
GO:0003677 IDA DNA binding
GO:0004003 IMP ATP-dependent DNA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0006281 IEA:IDA DNA repair
GO:0006302 IMP double-strand break repair
GO:0006310 IDA DNA recombination
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007004 IDA telomere maintenance via telomerase
GO:0007131 TAS reciprocal meiotic recombination
GO:0008270 IEA zinc ion binding
GO:0008408 IDA 3'-5' exonuclease activity
GO:0016020 IDA membrane
GO:0016887 IEA ATPase activity
GO:0030674 IDA protein binding, bridging
GO:0030870 IEA:IDA Mre11 complex
GO:0031954 IDA positive regulation of protein autophosphorylation
GO:0032508 IMP DNA duplex unwinding
GO:0033674 IDA positive regulation of kinase activity
GO:0035861 IDA site of double-strand break
GO:0045120 IEA pronucleus
GO:0090305 IDA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000020649 Rad50-001 protein_coding Mus_musculus 0 4656
ENSMUST00000128483 Rad50-002 nonsense_mediated_decay Mus_musculus 0 1853
ENSMUST00000124352 Rad50-005 protein_coding Mus_musculus 0 1664
ENSMUST00000152598 Rad50-003 processed_transcript Mus_musculus 0 407
ENSMUST00000126121 Rad50-004 processed_transcript Mus_musculus 0 272
ENSMUST00000105321 Nfic-001 protein_coding Mus_musculus 0.000000002 71
ENSMUST00000091246 Flcn-005 protein_coding Mus_musculus 0.0000003 64
ENSMUST00000148151 Flcn-003 retained_intron Mus_musculus 0.0000003 64
ENSMUST00000102697 Flcn-004 protein_coding Mus_musculus 0.0000003 64
ENSMUST00000157025 Ctr9-003 retained_intron Mus_musculus 0.0005 53
ENSMUST00000152019 Ctr9-002 retained_intron Mus_musculus 0.0005 53

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