Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Accession	Transcript Name	Contained in Gene	Tax ID	Strand	Position	Biotype
Transcript Info
Description:	ciliary neurotrophic factor receptor
ENST00000378980	CNTFR-001	ENSG00000122756	9606	-	9:34551432-34589737	protein_coding

Expression Patterns

Transcript ID	Adipose	Adrenal	Brain	Breast	Heart	Liver	Lung	Muscle	Ovary	Placenta	Testis
ENST00000378980	9.311±0.00	1.467±0.00	5.076±0.30	3.147±2.72	0.632±0.26	1.281±0.01	0.701±0.22	9.174±5.27	5.370±0.00	4.144±3.41	3.595±0.04

Conserved Regions
Region ID	Sub-Region	Region Type	Position
CIL_0002XA	CIL_0002XA_0001	CGP	9:34521040-34590140

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0001967	IEA	suckling behavior
GO:0003360	IEA	brainstem development
GO:0004897	IDA	ciliary neurotrophic factor receptor activity
GO:0005102	IPI	receptor binding
GO:0005515	IEA	protein binding
GO:0005886	IEA	plasma membrane
GO:0007165	NAS	signal transduction
GO:0007399	TAS	nervous system development
GO:0007548	IEA	sex differentiation
GO:0008284	IEA	positive regulation of cell proliferation
GO:0016020	IEA	membrane
GO:0019898	TAS	extrinsic component of membrane
GO:0019955	IPI	cytokine binding
GO:0031225	IEA	anchored component of membrane
GO:0043524	IEA	negative regulation of neuron apoptotic process
GO:0060538	IEA	skeletal muscle organ development
GO:0070120	IDA	ciliary neurotrophic factor-mediated signaling pathway
GO:0097059	IDA	CNTFR-CLCF1 complex

Homologs
ENSEMBL Accession	Gene Name	Biotype	Species	E-Value	Bit Score
ENSMUST00000102961	Cntfr-001	protein_coding	Mus_musculus	0	2333
ENSMUST00000102962	Cntfr-002	protein_coding	Mus_musculus	0	2259
ENSMUST00000064443	Cntfr-004	protein_coding	Mus_musculus	0	486
ENSMUST00000084701	Cntfr-003	protein_coding	Mus_musculus	0	407
ENSMUST00000151181	Cntfr-006	processed_transcript	Mus_musculus	0	377

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