C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: kalirin, RhoGEF kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000393496 KALRN-002 ENSG00000160145 9606 + 3:124504739-124675427 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalColonKidneyLiverOvaryPlacentaTestisENST00000393496
Transcript ID Adrenal Colon Kidney Liver Ovary Placenta Testis
ENST00000393496 4.210±0.00 1.371±0.00 1.772±0.00 2.769±0.00 2.359±0.00 2.480±0.48 3.315±1.49

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005085 TAS guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0006468 IEA protein phosphorylation
GO:0007165 TAS signal transduction
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007399 ISS nervous system development
GO:0015629 TAS actin cytoskeleton
GO:0016192 TAS vesicle-mediated transport
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0035556 ISS intracellular signal transduction
GO:0043065 TAS positive regulation of apoptotic process
GO:0043547 TAS positive regulation of GTPase activity
GO:0046872 IEA metal ion binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0070062 IDA extracellular vesicular exosome
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000114963 Kalrn-010 protein_coding Mus_musculus 0 2918
ENSMUST00000114964 Kalrn-014 protein_coding Mus_musculus 0 2501
ENSMUST00000114973 Kalrn-015 protein_coding Mus_musculus 0 2017
ENSMUST00000076810 Kalrn-011 protein_coding Mus_musculus 0 2017
ENSMUST00000114966 Kalrn-013 protein_coding Mus_musculus 0 2013
ENSMUST00000142817 Kalrn-009 protein_coding Mus_musculus 0 2013
ENSMUST00000114961 Kalrn-012 protein_coding Mus_musculus 0 774

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