C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: peroxisome proliferator-activated receptor gamma
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000397012 PPARG-001 ENSG00000132170 9606 + 3:12288838-12434344 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonLungOvaryPlacentaENST00000397012
Transcript ID Colon Lung Ovary Placenta
ENST00000397012 3.488±0.00 1.700±0.00 2.186±0.00 4.335±0.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001ZK CIL_0001ZK_0001 CGP 3:12153051-12434356
CIL_0004K9 CIL_0004K9_0001 CGP 3:12287368-12539623

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0001890 ISS placenta development
GO:0003677 ISS DNA binding
GO:0003682 ISS chromatin binding
GO:0003700 ISS:IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0004879 IEA:IDA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0004955 TAS prostaglandin receptor activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005829 ISS cytosol
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006629 TAS lipid metabolic process
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007165 IDA signal transduction
GO:0007186 TAS G-protein coupled receptor signaling pathway
GO:0007584 TAS response to nutrient
GO:0008144 IDA drug binding
GO:0008217 IMP regulation of blood pressure
GO:0008270 IEA zinc ion binding
GO:0010467 TAS gene expression
GO:0010745 IC negative regulation of macrophage derived foam cell differentiation
GO:0010871 IDA negative regulation of receptor biosynthetic process
GO:0010887 IDA negative regulation of cholesterol storage
GO:0010891 IDA negative regulation of sequestering of triglyceride
GO:0015909 ISS long-chain fatty acid transport
GO:0019899 IPI enzyme binding
GO:0030224 IDA monocyte differentiation
GO:0030374 IDA ligand-dependent nuclear receptor transcription coactivator activity
GO:0030522 IEA intracellular receptor signaling pathway
GO:0030855 ISS epithelial cell differentiation
GO:0032526 IDA response to retinoic acid
GO:0032869 IMP cellular response to insulin stimulus
GO:0033613 IDA activating transcription factor binding
GO:0033993 ISS response to lipid
GO:0035357 IMP peroxisome proliferator activated receptor signaling pathway
GO:0042593 IMP glucose homeostasis
GO:0042953 IDA lipoprotein transport
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA:IDA sequence-specific DNA binding
GO:0044212 ISS transcription regulatory region DNA binding
GO:0045087 TAS innate immune response
GO:0045165 ISS cell fate commitment
GO:0045600 ISS positive regulation of fat cell differentiation
GO:0045713 IDA low-density lipoprotein particle receptor biosynthetic process
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046965 IDA retinoid X receptor binding
GO:0048469 IDA cell maturation
GO:0048662 IDA negative regulation of smooth muscle cell proliferation
GO:0050544 ISS arachidonic acid binding
GO:0050872 ISS white fat cell differentiation
GO:0051091 IDA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0055088 TAS lipid homeostasis
GO:0055098 IDA response to low-density lipoprotein particle
GO:0060336 IMP negative regulation of interferon-gamma-mediated signaling pathway
GO:0060694 IC regulation of cholesterol transporter activity
GO:0060850 ISS regulation of transcription involved in cell fate commitment

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000171644 Pparg-202 protein_coding Mus_musculus 0 2135
ENSMUST00000000450 Pparg-201 protein_coding Mus_musculus 0 2128

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