C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000397195 PAFAH1B1-001 ENSG00000007168 9606 + 17:2593746-2685615 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000397195
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000397195 16.826±0.00 15.137±0.00 1.421±0.00 31.652±0.52 16.395±0.00 14.656±3.69 13.652±6.80 10.720±0.00 7.475±2.40 10.074±2.52 13.240±7.60 14.112±1.98 14.485±2.45 20.573±1.57

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00060V CIL_00060V_0002 CGP 17:2405562-2685615
CIL_00060W CIL_00060W_0002 CGP 17:2593210-2712663

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000132 IMP establishment of mitotic spindle orientation
GO:0000226 ISS microtubule cytoskeleton organization
GO:0000235 IDA astral microtubule
GO:0000278 TAS mitotic cell cycle
GO:0000776 IDA kinetochore
GO:0001667 IEA ameboidal cell migration
GO:0001675 ISS acrosome assembly
GO:0001764 ISS neuron migration
GO:0001961 IEA positive regulation of cytokine-mediated signaling pathway
GO:0005515 IPI:IEA protein binding
GO:0005635 IDA nuclear envelope
GO:0005737 IEA cytoplasm
GO:0005813 ISS centrosome
GO:0005829 ISS cytosol
GO:0005871 IEA kinesin complex
GO:0005875 IDA microtubule associated complex
GO:0005938 IDA cell cortex
GO:0007017 IDA microtubule-based process
GO:0007067 IEA mitotic nuclear division
GO:0007097 IEA nuclear migration
GO:0007268 ISS synaptic transmission
GO:0007405 ISS neuroblast proliferation
GO:0007420 IEA brain development
GO:0007611 ISS learning or memory
GO:0008017 ISS microtubule binding
GO:0008090 ISS retrograde axon cargo transport
GO:0008201 ISS heparin binding
GO:0008344 IMP adult locomotory behavior
GO:0009306 IEA protein secretion
GO:0010977 IEA negative regulation of neuron projection development
GO:0015630 IEA microtubule cytoskeleton
GO:0016020 IEA membrane
GO:0016042 IEA lipid catabolic process
GO:0016477 IEA cell migration
GO:0017145 IEA stem cell division
GO:0019226 ISS transmission of nerve impulse
GO:0021540 IMP corpus callosum morphogenesis
GO:0021766 ISS hippocampus development
GO:0021819 ISS layer formation in cerebral cortex
GO:0021895 IEA cerebral cortex neuron differentiation
GO:0021987 IMP cerebral cortex development
GO:0030036 ISS actin cytoskeleton organization
GO:0030424 IEA axon
GO:0030426 IEA growth cone
GO:0031023 IMP microtubule organizing center organization
GO:0031252 ISS cell leading edge
GO:0031512 ISS motile primary cilium
GO:0031982 IEA vesicle
GO:0032319 ISS regulation of Rho GTPase activity
GO:0032403 IEA protein complex binding
GO:0034452 ISS dynactin binding
GO:0036035 IEA osteoclast development
GO:0042803 ISS protein homodimerization activity
GO:0043005 IEA neuron projection
GO:0043025 IEA neuronal cell body
GO:0043274 ISS phospholipase binding
GO:0045502 IDA dynein binding
GO:0045505 IEA dynein intermediate chain binding
GO:0045773 IEA positive regulation of axon extension
GO:0045931 IEA positive regulation of mitotic cell cycle
GO:0046329 IEA negative regulation of JNK cascade
GO:0046469 ISS platelet activating factor metabolic process
GO:0047496 ISS vesicle transport along microtubule
GO:0048471 ISS perinuclear region of cytoplasm
GO:0048854 IMP brain morphogenesis
GO:0050885 IMP neuromuscular process controlling balance
GO:0051081 IEA nuclear envelope disassembly
GO:0051219 ISS phosphoprotein binding
GO:0051660 IEA establishment of centrosome localization
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000021091 Pafah1b1-002 protein_coding Mus_musculus 0 5450
ENSMUST00000102520 Pafah1b1-004 protein_coding Mus_musculus 0 5096
ENSMUST00000126341 Pafah1b1-005 retained_intron Mus_musculus 0 3121
ENSMUST00000156794 Pafah1b1-006 retained_intron Mus_musculus 0 3120
ENSDART00000031470 pafah1b1b-001 protein_coding Danio_rerio 0 1079
ENSDART00000042218 pafah1b1a-001 protein_coding Danio_rerio 0 1072
ENSMUST00000181263 Pafah1b1-ps1-001 processed_pseudogene Mus_musculus 0 643
ENSMUST00000155493 Pafah1b1-001 protein_coding Mus_musculus 0 625

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