C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: interferon regulatory factor 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000402030 IRF5-001 ENSG00000128604 9606 + 7:128937989-128950035 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBreastHeartOvaryENST00000402030
Transcript ID Adipose Breast Heart Ovary
ENST00000402030 0.493±0.00 0.431±0.00 0.227±0.00 1.077±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001YB CIL_0001YB_0001 CGP 7:128937612-129055144

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000975 IEA regulatory region DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0032494 IDA response to peptidoglycan
GO:0032495 IDA response to muramyl dipeptide
GO:0032727 IC positive regulation of interferon-alpha production
GO:0032728 IC positive regulation of interferon-beta production
GO:0032735 IC positive regulation of interleukin-12 production
GO:0043065 IMP positive regulation of apoptotic process
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000004392 Irf5-001 protein_coding Mus_musculus 0 1580
ENSMUST00000163511 Irf5-003 protein_coding Mus_musculus 0 1555
ENSMUST00000167252 Irf5-004 protein_coding Mus_musculus 0 566
ENSMUST00000164922 Irf5-006 processed_transcript Mus_musculus 0 331
ENSMUST00000164626 Irf5-002 protein_coding Mus_musculus 0 292
ENSMUST00000140066 Irf6-002 retained_intron Mus_musculus 0.00000000000006 84
ENSMUST00000138826 Irf6-004 retained_intron Mus_musculus 0.00000000000006 84
ENSMUST00000076521 Irf6-001 protein_coding Mus_musculus 0.00000000000006 84

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