C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: RAS guanyl releasing protein 3 (calcium and DAG-regulated)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000403687 RASGRP3-006 ENSG00000152689 9606 + 2:33476228-33564731 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastKidneyLiverLungMuscleOvaryPlacentaTestisENST00000403687
Transcript ID Adrenal Brain Breast Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000403687 1.324±0.00 1.656±0.24 0.610±0.00 0.558±0.00 0.340±0.00 0.971±0.00 1.793±0.00 0.384±0.00 0.382±0.12 0.084±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000MZ CIL_0000MZ_0001 CGP 2:32946972-33564750
CIL_0003TB CIL_0003TB_0002 CGP 2:33436324-33599382

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 NAS MAPK cascade
GO:0004871 TAS signal transducer activity
GO:0005085 TAS:IEA guanyl-nucleotide exchange factor activity
GO:0005088 IEA Ras guanyl-nucleotide exchange factor activity
GO:0005099 IEA Ras GTPase activator activity
GO:0005509 NAS:IEA calcium ion binding
GO:0005622 IEA intracellular
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0007264 TAS:IEA small GTPase mediated signal transduction
GO:0007265 IEA Ras protein signal transduction
GO:0017016 IEA Ras GTPase binding
GO:0019900 IEA kinase binding
GO:0019992 NAS diacylglycerol binding
GO:0032045 IEA guanyl-nucleotide exchange factor complex
GO:0032320 IEA positive regulation of Ras GTPase activity
GO:0032854 IDA positive regulation of Rap GTPase activity
GO:0035556 IEA intracellular signal transduction
GO:0043087 IEA regulation of GTPase activity
GO:0043547 TAS positive regulation of GTPase activity
GO:0046582 IDA Rap GTPase activator activity
GO:0048471 IEA perinuclear region of cytoplasm
GO:0051056 IEA regulation of small GTPase mediated signal transduction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000095204 Rasgrp3-201 protein_coding Mus_musculus 0 2748
ENSMUST00000164192 Rasgrp3-202 protein_coding Mus_musculus 0 2697

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