C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: lysine (K)-specific demethylase 5C
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000404049 KDM5C-009 ENSG00000126012 9606 - X:53192257-53225176 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000404049
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000404049 7.719±0.00 9.950±0.00 2.224±0.00 5.017±3.72 8.693±0.00 5.984±2.69 3.738±3.48 10.535±0.00 4.242±0.00 13.456±0.00 7.727±4.18 11.919±1.08 9.434±2.04 7.258±2.36

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0016706 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0032453 IDA histone demethylase activity (H3-K4 specific)
GO:0034720 IDA histone H3-K4 demethylation
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000112584 Kdm5c-002 protein_coding Mus_musculus 0 6793
ENSMUST00000112588 Kdm5c-001 protein_coding Mus_musculus 0 6754
ENSMUST00000082177 Kdm5c-004 protein_coding Mus_musculus 0 5999
ENSMUST00000055032 Kdm5d-001 protein_coding Mus_musculus 0 2423
ENSMUST00000187296 Kdm5d-008 retained_intron Mus_musculus 0 2303
ENSMUST00000186726 Kdm5d-002 nonsense_mediated_decay Mus_musculus 0 1386
ENSMUST00000154938 Kdm5c-003 retained_intron Mus_musculus 0 1336
ENSMUST00000186696 Kdm5d-003 nonsense_mediated_decay Mus_musculus 0 870
ENSDART00000098657 kdm5c-201 protein_coding Danio_rerio 0 782
ENSDART00000127053 kdm5c-001 protein_coding Danio_rerio 0 782
ENSMUST00000156114 Kdm5c-005 protein_coding Mus_musculus 0 651
ENSMUST00000155793 Kdm5c-006 protein_coding Mus_musculus 0 464

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