C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: midkine (neurite growth-promoting factor 2)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000405308 MDK-006 ENSG00000110492 9606 + 11:46380756-46383799 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartLiverLungMusclePlacentaENST00000405308
Transcript ID Adipose Adrenal Breast Colon Heart Liver Lung Muscle Placenta
ENST00000405308 5.516±0.00 3.489±0.00 1.092±0.00 3.523±0.00 1.215±0.00 1.201±0.00 1.242±0.00 0.983±0.00 6.433±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002US CIL_0002US_0003 CGP 11:46332905-46383837
CIL_0002LJ CIL_0002LJ_0002 CGP 11:46380756-46386608

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001662 IEA behavioral fear response
GO:0005576 TAS extracellular region
GO:0005737 IEA cytoplasm
GO:0007165 NAS signal transduction
GO:0007219 TAS Notch signaling pathway
GO:0007399 NAS nervous system development
GO:0007614 IEA short-term memory
GO:0008083 IEA:NAS growth factor activity
GO:0008201 IDA heparin binding
GO:0009611 ISS response to wounding
GO:0009725 IEA response to hormone
GO:0016477 IEA cell migration
GO:0021542 IEA dentate gyrus development
GO:0021681 IEA cerebellar granular layer development
GO:0021766 IEA hippocampus development
GO:0021987 IEA cerebral cortex development
GO:0030154 NAS cell differentiation
GO:0030325 ISS adrenal gland development
GO:0030421 IEA defecation
GO:0042493 IEA response to drug
GO:0042995 IEA cell projection
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0050795 IEA regulation of behavior
GO:0051384 IEA response to glucocorticoid
GO:0051781 IEA positive regulation of cell division
GO:1901215 IEA negative regulation of neuron death

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000111309 Mdk-004 protein_coding Mus_musculus 0 560
ENSMUST00000028672 Mdk-001 protein_coding Mus_musculus 0 560
ENSMUST00000069423 Mdk-002 protein_coding Mus_musculus 0 556
ENSMUST00000090602 Mdk-003 protein_coding Mus_musculus 0 518

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