C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: solute carrier family 8 (sodium/calcium exchanger), member 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000406785 SLC8A1-005 ENSG00000183023 9606 - 2:40097270-40452069 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000406785
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000406785 0.512±0.00 1.137±0.00 4.021±2.92 0.565±0.31 0.790±0.36 4.881±0.00 0.259±0.00 2.661±0.00 0.552±0.15 0.035±0.01 0.168±0.07 0.445±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00066Z CIL_00066Z_0001 CGP 2:39736060-40611053

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002026 ISS regulation of the force of heart contraction
GO:0002027 ISS regulation of heart rate
GO:0005432 IDA:IEA calcium:sodium antiporter activity
GO:0005516 IEA calmodulin binding
GO:0005886 TAS plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0006811 TAS ion transport
GO:0006816 IEA calcium ion transport
GO:0006883 IDA cellular sodium ion homeostasis
GO:0006936 TAS muscle contraction
GO:0007154 IEA cell communication
GO:0007596 TAS blood coagulation
GO:0008092 IDA cytoskeletal protein binding
GO:0010881 ISS regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0010882 TAS regulation of cardiac muscle contraction by calcium ion signaling
GO:0014704 ISS intercalated disc
GO:0014829 ISS vascular smooth muscle contraction
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030018 ISS Z disc
GO:0030315 ISS T-tubule
GO:0030506 ISS ankyrin binding
GO:0034614 IDA cellular response to reactive oxygen species
GO:0035725 IEA sodium ion transmembrane transport
GO:0042383 ISS sarcolemma
GO:0044325 ISS ion channel binding
GO:0044557 ISS relaxation of smooth muscle
GO:0046872 IEA metal ion binding
GO:0051481 ISS negative regulation of cytosolic calcium ion concentration
GO:0055013 ISS cardiac muscle cell development
GO:0055074 ISS calcium ion homeostasis
GO:0055085 TAS:IEA transmembrane transport
GO:0055119 IC relaxation of cardiac muscle
GO:0060048 TAS cardiac muscle contraction
GO:0060401 TAS cytosolic calcium ion transport
GO:0060402 ISS calcium ion transport into cytosol
GO:0070509 IDA calcium ion import
GO:0071313 ISS cellular response to caffeine
GO:0071436 IDA sodium ion export
GO:0086012 TAS membrane depolarization during cardiac muscle cell action potential
GO:0086064 ISS cell communication by electrical coupling involved in cardiac conduction
GO:0097369 IDA sodium ion import
GO:1901660 IDA calcium ion export

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000163123 Slc8a1-202 protein_coding Mus_musculus 0 2143
ENSMUST00000086538 Slc8a1-201 protein_coding Mus_musculus 0 2143
ENSMUST00000163680 Slc8a1-203 protein_coding Mus_musculus 0 2143

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