C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cullin 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000409096 CUL3-002 ENSG00000036257 9606 - 2:224473922-224569825 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000409096
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000409096 12.673±0.00 2.445±0.00 8.343±3.16 8.841±2.93 2.163±0.00 8.229±4.97 9.683±5.68 5.971±1.03 6.911±2.23 24.106±0.00 14.325±10.24 5.114±2.19 203.452±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006XN CIL_0006XN_0001 CGP 2:224378698-224585397
CIL_0006XM CIL_0006XM_0001 CGP 2:224470150-225042445

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000139 IMP Golgi membrane
GO:0000209 IDA protein polyubiquitination
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005827 IDA polar microtubule
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0006513 IDA protein monoubiquitination
GO:0006888 IDA ER to Golgi vesicle-mediated transport
GO:0007050 TAS cell cycle arrest
GO:0007080 IMP mitotic metaphase plate congression
GO:0007229 ISS integrin-mediated signaling pathway
GO:0008054 IDA cyclin catabolic process
GO:0008284 TAS positive regulation of cell proliferation
GO:0016020 IDA membrane
GO:0016477 IMP cell migration
GO:0016567 IDA protein ubiquitination
GO:0017145 ISS stem cell division
GO:0031208 IDA POZ domain binding
GO:0031461 IEA cullin-RING ubiquitin ligase complex
GO:0031463 IDA Cul3-RING ubiquitin ligase complex
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032467 IMP positive regulation of cytokinesis
GO:0035024 IMP negative regulation of Rho protein signal transduction
GO:0040016 ISS embryonic cleavage
GO:0043149 IMP stress fiber assembly
GO:0043161 IDA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045842 IMP positive regulation of mitotic metaphase/anaphase transition
GO:0048208 IMP COPII vesicle coating
GO:0070062 IDA extracellular vesicular exosome
GO:0097193 TAS intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000163119 Cul3-001 protein_coding Mus_musculus 0 3919
ENSMUST00000164108 Cul3-002 protein_coding Mus_musculus 0 3561
ENSMUST00000167794 Cul3-006 retained_intron Mus_musculus 0 771
ENSMUST00000170897 Cul3-003 nonsense_mediated_decay Mus_musculus 0 743
ENSMUST00000168372 Cul3-005 protein_coding Mus_musculus 0 538
ENSMUST00000167293 Cul3-004 nonsense_mediated_decay Mus_musculus 0 477
ENSDART00000125379 protein_coding Danio_rerio 3e-37 161

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