C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: major histocompatibility complex, class II, DM beta
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000418107 HLA-DMB-001 ENSG00000242574 9606 - 6:32934629-32941070 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastHeartLiverLungOvaryPlacentaENST00000418107
Transcript ID Breast Heart Liver Lung Ovary Placenta
ENST00000418107 33.132±0.00 6.143±0.00 11.400±0.00 54.058±0.00 18.980±0.00 40.277±1.64

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001PK CIL_0001PK_0004 CGP 6:32934629-32953122

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002399 IMP MHC class II protein complex assembly
GO:0002503 IDA peptide antigen assembly with MHC class II protein complex
GO:0005515 IEA protein binding
GO:0005765 TAS lysosomal membrane
GO:0005768 IEA endosome
GO:0006955 IEA immune response
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019882 IEA antigen processing and presentation
GO:0019886 IMP antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0023026 IDA MHC class II protein complex binding
GO:0042102 IMP positive regulation of T cell proliferation
GO:0042613 IDA:IEA MHC class II protein complex
GO:2001190 IMP positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000041982 H2-DMb2-001 protein_coding Mus_musculus 0 556
ENSMUST00000114232 H2-DMb1-001 protein_coding Mus_musculus 0 553
ENSMUST00000171231 H2-DMb2-002 protein_coding Mus_musculus 0 540
ENSMUST00000174765 H2-DMb1-002 processed_transcript Mus_musculus 0 351

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