C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: forkhead box A2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000419308 FOXA2-002 ENSG00000125798 9606 - 20:22581005-22584463 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastLungOvaryENST00000419308
Transcript ID Breast Lung Ovary
ENST00000419308 0.762±0.00 1.750±0.67 8.995±4.93

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002XI CIL_0002XI_0001 CGP 20:21705659-22585455
CIL_0001U5 CIL_0001U5_0001 CGP 20:22581005-23036812

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000432 ISS positive regulation of transcription from RNA polymerase II promoter by glucose
GO:0000433 ISS negative regulation of transcription from RNA polymerase II promoter by glucose
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001205 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001701 IEA in utero embryonic development
GO:0001705 IEA ectoderm formation
GO:0001708 ISS cell fate specification
GO:0003677 IDA DNA binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0003705 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0007389 IEA pattern specification process
GO:0008134 IEA transcription factor binding
GO:0008344 ISS adult locomotory behavior
GO:0009653 IEA anatomical structure morphogenesis
GO:0009952 IEA anterior/posterior pattern specification
GO:0009953 IEA dorsal/ventral pattern formation
GO:0010468 IEA regulation of gene expression
GO:0010719 IMP negative regulation of epithelial to mesenchymal transition
GO:0016568 IEA chromatin modification
GO:0019216 IEA regulation of lipid metabolic process
GO:0019218 IEA regulation of steroid metabolic process
GO:0019904 IEA protein domain specific binding
GO:0021533 IEA cell differentiation in hindbrain
GO:0021904 IEA dorsal/ventral neural tube patterning
GO:0023019 IEA signal transduction involved in regulation of gene expression
GO:0030193 IDA regulation of blood coagulation
GO:0030324 IEA lung development
GO:0031018 IDA endocrine pancreas development
GO:0032525 IEA somite rostral/caudal axis specification
GO:0033132 ISS negative regulation of glucokinase activity
GO:0040019 ISS positive regulation of embryonic development
GO:0043433 IMP negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IMP transcription regulatory region DNA binding
GO:0045665 IEA negative regulation of neuron differentiation
GO:0045666 IEA positive regulation of neuron differentiation
GO:0045880 IEA positive regulation of smoothened signaling pathway
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0045945 IEA positive regulation of transcription from RNA polymerase III promoter
GO:0048468 IEA cell development
GO:0048646 IEA anatomical structure formation involved in morphogenesis
GO:0048665 IEA neuron fate specification
GO:0060441 IEA epithelial tube branching involved in lung morphogenesis
GO:0060487 IEA lung epithelial cell differentiation
GO:0061178 ISS regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0061448 IEA connective tissue development
GO:0070741 TAS response to interleukin-6
GO:0071542 ISS dopaminergic neuron differentiation
GO:0090009 ISS primitive streak formation
GO:2000049 IC positive regulation of cell-cell adhesion mediated by cadherin
GO:2000543 ISS positive regulation of gastrulation
GO:2000971 ISS negative regulation of detection of glucose
GO:2000976 ISS regulation of transcription from RNA polymerase II promoter involved in detection of glucose

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000109964 Foxa2-002 protein_coding Mus_musculus 0 1903
ENSMUST00000047315 Foxa2-001 protein_coding Mus_musculus 0 1816
ENSMUST00000172928 Foxa2-004 protein_coding Mus_musculus 0 917
ENSMUST00000146242 Foxa2-003 processed_transcript Mus_musculus 0 839
ENSMUST00000044380 Foxa1-201 protein_coding Mus_musculus 0 449
ENSDART00000010813 foxa3-001 protein_coding Danio_rerio 0 281

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