C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cylindromatosis (turban tumor syndrome)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000427738 CYLD-010 ENSG00000083799 9606 + 16:50742760-50801935 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonLiverLungMuscleOvaryPlacentaTestisENST00000427738
Transcript ID Adipose Brain Breast Colon Liver Lung Muscle Ovary Placenta Testis
ENST00000427738 0.991±0.00 3.186±1.97 1.676±0.00 1.660±0.39 0.553±0.00 3.904±0.00 0.787±0.25 2.056±0.39 1.903±0.64 2.997±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ON CIL_0007ON_0001 UCNEbase 16:50459337-51906374
CIL_00090I CIL_00090I_0001 VISTA 16:50514444-51115745
CIL_00085B CIL_00085B_0001 VISTA 16:50535781-51137187
CIL_00090J CIL_00090J_0001 VISTA 16:50540952-51141798
CIL_00090K CIL_00090K_0001 VISTA 16:50643117-51244272
CIL_00090L CIL_00090L_0001 VISTA 16:50648118-51248778
CIL_00090M CIL_00090M_0001 VISTA 16:50676779-51277697
CIL_0003PR CIL_0003PR_0001 CGP 16:50693603-50801935
CIL_00090N CIL_00090N_0001 VISTA 16:50708342-51309204
CIL_0008AU CIL_0008AU_0001 VISTA 16:50722400-51323681
CIL_00077S CIL_00077S_0001 CGP 16:50742050-51151367

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004843 IDA ubiquitin-specific protease activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005813 IDA centrosome
GO:0005829 IDA cytosol
GO:0005881 IDA cytoplasmic microtubule
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0007049 IEA cell cycle
GO:0007346 IMP regulation of mitotic cell cycle
GO:0008270 IDA zinc ion binding
GO:0016055 IEA Wnt signaling pathway
GO:0016579 IEA protein deubiquitination
GO:0019901 IPI protein kinase binding
GO:0030496 IDA midbody
GO:0031234 IDA extrinsic component of cytoplasmic side of plasma membrane
GO:0032088 IDA negative regulation of NF-kappaB transcription factor activity
GO:0032480 TAS negative regulation of type I interferon production
GO:0035872 TAS nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0036459 IEA ubiquitinyl hydrolase activity
GO:0042347 IDA negative regulation of NF-kappaB import into nucleus
GO:0045087 TAS innate immune response
GO:0045581 IEA negative regulation of T cell differentiation
GO:0061578 IDA Lys63-specific deubiquitinase activity
GO:0070064 IPI proline-rich region binding
GO:0070266 IBA necroptotic process
GO:0070423 TAS nucleotide-binding oligomerization domain containing signaling pathway
GO:0070507 IMP regulation of microtubule cytoskeleton organization
GO:0070536 IDA protein K63-linked deubiquitination
GO:0090090 IMP negative regulation of canonical Wnt signaling pathway
GO:1901026 IEA ripoptosome assembly involved in necroptotic process
GO:2001238 IMP positive regulation of extrinsic apoptotic signaling pathway
GO:2001242 IMP regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000098519 Cyld-202 protein_coding Mus_musculus 0 4281
ENSMUST00000043526 Cyld-201 protein_coding Mus_musculus 0 4270
ENSMUST00000109626 Cyld-203 protein_coding Mus_musculus 0 4228
ENSMUST00000191467 RP23-303B4.1-001 processed_pseudogene Mus_musculus 0 1380

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