C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: acid-sensing (proton-gated) ion channel 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000447966 ASIC1-002 ENSG00000110881 9606 + 12:50057704-50083611 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000447966
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000447966 1.217±0.00 0.190±0.00 9.567±0.00 1.495±0.00 1.216±1.20 0.272±0.00 0.211±0.20 0.034±0.00 0.105±0.00 1.404±0.85 0.558±0.19 0.608±0.12

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008PE CIL_0008PE_0001 VISTA 12:49905565-50507504
CIL_0008CC CIL_0008CC_0001 VISTA 12:49906068-50507455
CIL_00071Y CIL_00071Y_0001 CGP 12:49976923-50083611

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005272 IEA sodium channel activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 ISS integral component of plasma membrane
GO:0006810 TAS transport
GO:0006814 NAS:IEA sodium ion transport
GO:0007165 TAS signal transduction
GO:0009268 TAS response to pH
GO:0015280 TAS:IEA ligand-gated sodium channel activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0034220 TAS ion transmembrane transport
GO:0035725 ISS sodium ion transmembrane transport
GO:0044736 ISS acid-sensing ion channel activity
GO:0050915 IMP sensory perception of sour taste
GO:0055085 TAS transmembrane transport
GO:0070207 ISS protein homotrimerization
GO:0071467 IDA cellular response to pH

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000023758 Asic1-201 protein_coding Mus_musculus 0 3522
ENSDART00000028603 asic1b-201 protein_coding Danio_rerio 0 634
ENSDART00000140236 asic1b-001 protein_coding Danio_rerio 0 634
ENSDART00000105541 asic1a-201 protein_coding Danio_rerio 0 521
ENSDART00000004588 asic1a-001 protein_coding Danio_rerio 0 521

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