C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: acid-sensing (proton-gated) ion channel 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000110881 ASIC1 9606 + 12:50057548-50083611 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000228468 ASIC1-001 50057548-50083611 protein_coding
  ENST00000447966 ASIC1-002 50057704-50083611 protein_coding
  ENST00000453327 ASIC1-007 50059887-50081940 protein_coding
  ENST00000548350 ASIC1-006 50078462-50079942 retained_intron
  ENST00000549792 ASIC1-005 50076750-50077262 retained_intron
  ENST00000550558 ASIC1-003 50057745-50083611 nonsense_mediated_decay
  ENST00000551199 ASIC1-004 50070740-50080782 retained_intron
  ENST00000552438 ASIC1-009 50073575-50083277 protein_coding
  ENST00000552633 ASIC1-008 50080498-50082818 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000447966ENST00000453327ENST00000550558ENST00000551199ENST00000552438ENST00000552633
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000447966 N/A 1.217±0.00 0.190±0.00 9.567±0.00 1.495±0.00 1.216±1.20 0.272±0.00 0.211±0.20 0.034±0.00 0.105±0.00 1.404±0.85 0.558±0.19 0.608±0.12
ENST00000453327 N/A N/A N/A 1.117±0.00 N/A N/A N/A N/A N/A 0.813±0.00 N/A N/A N/A
ENST00000550558 N/A N/A N/A 0.461±0.00 N/A 0.419±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000551199 N/A N/A N/A N/A N/A 0.205±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000552438 0.024±0.00 N/A N/A N/A N/A N/A N/A N/A 0.005±0.00 N/A 0.291±0.00 N/A N/A
ENST00000552633 N/A N/A N/A N/A N/A N/A 0.325±0.09 N/A N/A N/A 3.054±0.00 1.719±0.00 1.516±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008PE CIL_0008PE_0001 VISTA 12:49905565-50507504
CIL_0008CC CIL_0008CC_0001 VISTA 12:49906068-50507455
CIL_00071Y CIL_00071Y_0001 CGP 12:49976923-50083611

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005261 IEA cation channel activity
GO:0005272 IEA sodium channel activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006810 TAS transport
GO:0006812 IEA cation transport
GO:0006814 IEA sodium ion transport
GO:0007165 TAS signal transduction
GO:0007613 IEA memory
GO:0008306 IEA associative learning
GO:0009268 TAS response to pH
GO:0010447 IEA response to acidic pH
GO:0015280 TAS:IEA ligand-gated sodium channel activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0022839 IEA ion gated channel activity
GO:0034220 IEA ion transmembrane transport
GO:0035725 ISS sodium ion transmembrane transport
GO:0042391 IEA regulation of membrane potential
GO:0044736 ISS acid-sensing ion channel activity
GO:0045202 IEA synapse
GO:0046929 IEA negative regulation of neurotransmitter secretion
GO:0050915 IMP sensory perception of sour taste
GO:0055085 TAS transmembrane transport
GO:0070207 ISS protein homotrimerization
GO:0070588 IEA calcium ion transmembrane transport
GO:0071467 IDA cellular response to pH

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008329 asic1a acid-sensing (proton-gated) ion channel 1a protein_coding Danio_rerio
ENSDARG00000071637 ASIC1 (2 of 2) acid-sensing (proton-gated) ion channel 1 protein_coding Danio_rerio
ENSMUSG00000023017 Asic1 acid-sensing (proton-gated) ion channel 1 protein_coding Mus_musculus

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