C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: acid-sensing (proton-gated) ion channel 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000023758 Asic1-201 ENSMUSG00000023017 10090 + 15:99670718-99701127 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023758
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023758 0.590±0.06 0.537±0.00 23.629±9.87 0.714±0.14 0.158±0.04 0.551±0.26 0.652±0.00 0.368±0.10 0.604±0.05 0.036±0.00 0.411±0.18 0.372±0.03 0.292±0.14

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008PE CIL_0008PE_0002 VISTA 15:99507076-100109694
CIL_0008CC CIL_0008CC_0002 VISTA 15:99507743-100109214
CIL_00071Y CIL_00071Y_0002 CGP 15:99620496-99701127

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005261 IDA cation channel activity
GO:0005515 IPI protein binding
GO:0005887 IDA integral component of plasma membrane
GO:0006812 IDA cation transport
GO:0007613 IMP memory
GO:0008306 IMP associative learning
GO:0010447 IDA response to acidic pH
GO:0022839 IDA ion gated channel activity
GO:0034220 IDA ion transmembrane transport
GO:0035725 ISS sodium ion transmembrane transport
GO:0042391 IMP regulation of membrane potential
GO:0044736 ISS acid-sensing ion channel activity
GO:0045202 IDA synapse
GO:0046929 IMP negative regulation of neurotransmitter secretion
GO:0070207 ISS protein homotrimerization
GO:0070588 IMP calcium ion transmembrane transport
GO:0071467 ISS cellular response to pH

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000105541 asic1a-201 protein_coding Danio_rerio 0 494
ENSDART00000004588 asic1a-001 protein_coding Danio_rerio 0 494
ENST00000228468 ASIC1-001 protein_coding Homo_sapiens 0 1978
ENST00000447966 ASIC1-002 protein_coding Homo_sapiens 0 3522
ENST00000453327 ASIC1-007 protein_coding Homo_sapiens 0 1489
ENST00000550558 ASIC1-003 nonsense_mediated_decay Homo_sapiens 0 2555
ENST00000551199 ASIC1-004 retained_intron Homo_sapiens 0 872
ENST00000552438 ASIC1-009 protein_coding Homo_sapiens 0 2442
ENST00000552633 ASIC1-008 protein_coding Homo_sapiens 0 545

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