C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: glutamate receptor, ionotropic, AMPA 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000448073 GRIA1-014 ENSG00000155511 9606 + 5:153492172-153811272 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonKidneyMuscleOvaryTestisENST00000448073
Transcript ID Colon Kidney Muscle Ovary Testis
ENST00000448073 0.146±0.00 0.250±0.00 0.315±0.00 0.087±0.04 1.190±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001UF CIL_0001UF_0001 CGP 5:152391532-153813869
CIL_0001UG CIL_0001UG_0001 CGP 5:153489615-154038936

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004970 IEA ionotropic glutamate receptor activity
GO:0004971 IDA alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:0005234 IBA:IEA extracellular-glutamate-gated ion channel activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0007165 TAS signal transduction
GO:0007268 TAS synaptic transmission
GO:0008066 TAS glutamate receptor activity
GO:0009986 ISS cell surface
GO:0014069 ISS postsynaptic density
GO:0016020 IEA membrane
GO:0030054 IEA cell junction
GO:0030165 ISS PDZ domain binding
GO:0030425 ISS dendrite
GO:0030666 TAS endocytic vesicle membrane
GO:0032281 ISS alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0034220 IEA ion transmembrane transport
GO:0035235 IEA ionotropic glutamate receptor signaling pathway
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0043025 ISS neuronal cell body
GO:0043197 ISS dendritic spine
GO:0044309 ISS neuron spine
GO:0045211 IBA postsynaptic membrane

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000151045 Gria1-006 protein_coding Mus_musculus 0 3518
ENSMUST00000036315 Gria1-004 protein_coding Mus_musculus 0 3518
ENSMUST00000094179 Gria1-005 protein_coding Mus_musculus 0 3319
ENSMUST00000107745 Gria2-202 protein_coding Mus_musculus 0 773
ENSMUST00000173531 Gria1-007 processed_transcript Mus_musculus 0 505
ENSMUST00000125292 Gria1-003 protein_coding Mus_musculus 0 191

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