C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: BRCA1 associated RING domain 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000449967 BARD1-201 ENSG00000138376 9606 - 2:214728553-214809642 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartKidneyMuscleOvaryENST00000449967
Transcript ID Heart Kidney Muscle Ovary
ENST00000449967 0.225±0.00 0.302±0.00 0.321±0.00 1.054±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000AI CIL_0000AI_0002 CGP 2:214411065-214809711
CIL_0000AP CIL_0000AP_0002 CGP 2:214725646-215138428

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000151 NAS ubiquitin ligase complex
GO:0001894 TAS tissue homeostasis
GO:0003723 IDA RNA binding
GO:0004842 NAS ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0006281 IEA DNA repair
GO:0006974 NAS cellular response to DNA damage stimulus
GO:0007050 NAS cell cycle arrest
GO:0008270 IEA zinc ion binding
GO:0016567 NAS protein ubiquitination
GO:0016874 IEA ligase activity
GO:0019900 NAS kinase binding
GO:0031436 IDA BRCA1-BARD1 complex
GO:0031441 NAS negative regulation of mRNA 3'-end processing
GO:0042325 IMP regulation of phosphorylation
GO:0042803 IPI protein homodimerization activity
GO:0043065 IMP positive regulation of apoptotic process
GO:0043066 IMP negative regulation of apoptotic process
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0045732 NAS positive regulation of protein catabolic process
GO:0046826 IDA negative regulation of protein export from nucleus
GO:0046982 IPI protein heterodimerization activity
GO:0070531 IDA BRCA1-A complex
GO:0085020 IDA protein K6-linked ubiquitination

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000027393 Bard1-001 protein_coding Mus_musculus 0 1349

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