C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: GLI family zinc finger 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000452319 GLI2-009 ENSG00000074047 9606 + 2:120792409-120992653 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00081M CIL_00081M_0001 VISTA 2:120504710-121107153
CIL_00081M CIL_00081M_0002 VISTA 2:120507154-121108132

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001501 ISS skeletal system development
GO:0001649 IDA osteoblast differentiation
GO:0001701 IEA in utero embryonic development
GO:0001822 ISS kidney development
GO:0002009 IEA morphogenesis of an epithelium
GO:0002062 IEA chondrocyte differentiation
GO:0002076 ISS osteoblast development
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005929 IEA cilium
GO:0006351 IEA transcription, DNA-templated
GO:0007224 IDA smoothened signaling pathway
GO:0007389 ISS pattern specification process
GO:0007411 ISS axon guidance
GO:0007418 ISS ventral midline development
GO:0007442 ISS hindgut morphogenesis
GO:0007507 ISS heart development
GO:0008270 IDA zinc ion binding
GO:0008283 IDA cell proliferation
GO:0008284 IEA positive regulation of cell proliferation
GO:0008589 IEA regulation of smoothened signaling pathway
GO:0009612 IEA response to mechanical stimulus
GO:0009913 IDA epidermal cell differentiation
GO:0009953 IEA dorsal/ventral pattern formation
GO:0009954 ISS proximal/distal pattern formation
GO:0016020 IEA membrane
GO:0016607 IEA nuclear speck
GO:0021508 ISS floor plate formation
GO:0021513 ISS spinal cord dorsal/ventral patterning
GO:0021517 ISS ventral spinal cord development
GO:0021522 IEA spinal cord motor neuron differentiation
GO:0021696 ISS cerebellar cortex morphogenesis
GO:0021775 ISS smoothened signaling pathway involved in ventral spinal cord interneuron specification
GO:0021776 IEA smoothened signaling pathway involved in spinal cord motor neuron cell fate specification
GO:0021904 IEA dorsal/ventral neural tube patterning
GO:0021915 IEA neural tube development
GO:0021938 IEA smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
GO:0021965 ISS spinal cord ventral commissure morphogenesis
GO:0021983 ISS pituitary gland development
GO:0030154 IEA cell differentiation
GO:0030324 ISS lung development
GO:0030879 ISS mammary gland development
GO:0030902 ISS hindbrain development
GO:0031512 IEA motile primary cilium
GO:0032331 IEA negative regulation of chondrocyte differentiation
GO:0033089 ISS positive regulation of T cell differentiation in thymus
GO:0035295 ISS tube development
GO:0042475 ISS odontogenesis of dentin-containing tooth
GO:0042733 IEA embryonic digit morphogenesis
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045666 IEA positive regulation of neuron differentiation
GO:0045740 IDA positive regulation of DNA replication
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0048566 ISS embryonic digestive tract development
GO:0048589 ISS developmental growth
GO:0048646 IEA anatomical structure formation involved in morphogenesis
GO:0048666 ISS neuron development
GO:0048754 ISS branching morphogenesis of an epithelial tube
GO:0048856 IEA anatomical structure development
GO:0060032 IEA notochord regression
GO:0060322 IEA head development
GO:0060513 IEA prostatic bud formation
GO:0060603 IEA mammary gland duct morphogenesis
GO:0060831 IEA smoothened signaling pathway involved in dorsal/ventral neural tube patterning
GO:0071407 IEA cellular response to organic cyclic compound
GO:0072372 IEA primary cilium
GO:0090103 IEA cochlea morphogenesis
GO:0097542 IEA ciliary tip
GO:0098586 IDA cellular response to virus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000062483 Gli2-001 protein_coding Mus_musculus 0 2263
ENSMUST00000161301 Gli2-002 protein_coding Mus_musculus 0 1098
ENSMUST00000160991 Gli2-006 nonsense_mediated_decay Mus_musculus 0 1000
ENSMUST00000162607 Gli2-008 protein_coding Mus_musculus 0 752
ENSMUST00000161056 Gli2-005 nonsense_mediated_decay Mus_musculus 0 752
ENSDART00000017912 gli2b-201 protein_coding Danio_rerio 0 617
ENSMUST00000161451 Gli2-004 protein_coding Mus_musculus 0 558
ENSMUST00000159839 Gli2-007 nonsense_mediated_decay Mus_musculus 0 558
ENSDART00000123101 gli1-202 protein_coding Danio_rerio 0 405
ENSDART00000049151 gli1-201 protein_coding Danio_rerio 0 405
ENSDART00000024555 gli2a-001 protein_coding Danio_rerio 0 353
ENSMUST00000162552 Gli2-003 nonsense_mediated_decay Mus_musculus 0 309

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