C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: patatin-like phospholipase domain containing 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000453144 PNPLA8-004 ENSG00000135241 9606 - 7:108471627-108526315 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartLiverLungOvaryENST00000453144
Transcript ID Bladder Brain Breast Colon Heart Liver Lung Ovary
ENST00000453144 1.944±0.00 5.008±1.05 3.205±0.00 6.959±0.00 4.683±0.00 4.082±0.00 9.734±0.00 4.354±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008PF CIL_0008PF_0001 VISTA 7:108074195-108676805
CIL_0008CE CIL_0008CE_0001 VISTA 7:108074285-108676732

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001516 IDA prostaglandin biosynthetic process
GO:0004622 IEA lysophospholipase activity
GO:0005488 IEA binding
GO:0005524 NAS ATP binding
GO:0005622 IDA intracellular
GO:0005777 IDA peroxisome
GO:0005778 IDA peroxisomal membrane
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005794 IEA Golgi apparatus
GO:0006629 IEA lipid metabolic process
GO:0006631 IDA fatty acid metabolic process
GO:0006644 TAS phospholipid metabolic process
GO:0008152 IEA metabolic process
GO:0008219 IDA cell death
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0019369 IDA arachidonic acid metabolic process
GO:0034638 IDA phosphatidylcholine catabolic process
GO:0036151 TAS phosphatidylcholine acyl-chain remodeling
GO:0036152 TAS phosphatidylethanolamine acyl-chain remodeling
GO:0043651 IDA linoleic acid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046338 IDA phosphatidylethanolamine catabolic process
GO:0046474 TAS glycerophospholipid biosynthetic process
GO:0047499 IDA calcium-independent phospholipase A2 activity
GO:0050482 IDA arachidonic acid secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000043082 Pnpla8-001 protein_coding Mus_musculus 0 2316
ENSMUST00000122902 Pnpla8-002 protein_coding Mus_musculus 0 1832
ENSMUST00000143771 Pnpla8-003 protein_coding Mus_musculus 0 1506
ENSMUST00000156082 Pnpla8-005 protein_coding Mus_musculus 0 475

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