C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: roundabout, axon guidance receptor, homolog 2 (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000461745 ROBO2-002 ENSG00000185008 9606 + 3:77039886-77649964 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainHeartLungOvaryTestisENST00000461745
Transcript ID Adrenal Brain Heart Lung Ovary Testis
ENST00000461745 0.030±0.00 1.702±0.00 0.015±0.00 0.922±0.00 0.192±0.05 0.139±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001656 ISS metanephros development
GO:0001657 IMP ureteric bud development
GO:0005515 IPI:IEA protein binding
GO:0007156 IDA homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007411 ISS axon guidance
GO:0007417 NAS central nervous system development
GO:0007420 IEP brain development
GO:0008046 ISS axon guidance receptor activity
GO:0009986 IDA cell surface
GO:0016021 IEA integral component of membrane
GO:0016199 ISS axon midline choice point recognition
GO:0021891 ISS olfactory bulb interneuron development
GO:0030673 ISS axolemma
GO:0031290 ISS retinal ganglion cell axon guidance
GO:0032870 IEP cellular response to hormone stimulus
GO:0042802 IDA identical protein binding
GO:0050772 IDA positive regulation of axonogenesis
GO:0050925 IDA negative regulation of negative chemotaxis
GO:0051964 ISS negative regulation of synapse assembly
GO:0061364 IEP apoptotic process involved in luteolysis
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000117200 Robo2-004 protein_coding Mus_musculus 0 6892
ENSMUST00000116586 Robo2-002 protein_coding Mus_musculus 0 4907
ENSMUST00000117785 Robo2-001 protein_coding Mus_musculus 0 3980
ENSMUST00000149114 Robo2-003 retained_intron Mus_musculus 0 1489
ENSMUST00000140062 Robo2-005 retained_intron Mus_musculus 0 1240
ENSMUST00000156010 Robo2-006 retained_intron Mus_musculus 0 955
ENSMUST00000138852 Robo2-008 retained_intron Mus_musculus 0 545
ENSMUST00000147408 Robo2-007 processed_transcript Mus_musculus 0 383

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