C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transducer of ERBB2, 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000499247 TOB1-001 ENSG00000141232 9606 - 17:50862223-50866345 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000499247
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000499247 4.490±0.00 7.767±0.00 4.509±1.58 6.158±0.58 4.854±4.40 18.551±0.00 5.850±3.30 3.362±2.06 16.219±10.49 7.615±6.92 1.606±0.69 9.838±7.67

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007KM CIL_0007KM_0001 UCNEbase 17:50750455-50862724
CIL_0004X3 CIL_0004X3_0003 CGP 17:50834650-50867978
CIL_0004X0 CIL_0004X0_0003 CGP 17:50862223-51120865

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003714 IEA transcription corepressor activity
GO:0005070 TAS SH3/SH2 adaptor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0007184 IEA SMAD protein import into nucleus
GO:0008285 IDA negative regulation of cell proliferation
GO:0009967 TAS positive regulation of signal transduction
GO:0017148 IDA negative regulation of translation
GO:0030014 IDA CCR4-NOT complex
GO:0030514 IEA negative regulation of BMP signaling pathway
GO:0030971 IDA receptor tyrosine kinase binding
GO:0045668 IEA negative regulation of osteoblast differentiation
GO:0046332 IEA SMAD binding
GO:0060212 IDA negative regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0060213 IDA positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:1900153 IDA positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:2001141 IEA regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000041589 Tob1-001 protein_coding Mus_musculus 0 2647
ENSDART00000049240 tob1a-001 protein_coding Danio_rerio 0 425
ENSDART00000022688 tob1b-001 protein_coding Danio_rerio 0 309

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