C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: hydroxysteroid (17-beta) dehydrogenase 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000515320 HSD17B4-002 ENSG00000133835 9606 + 5:119452497-119542252 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENST00000515320
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENST00000515320 28.060±0.00 10.615±0.00 16.852±0.00 19.392±0.00 11.476±0.00 20.843±0.00 28.308±0.00 54.639±0.00 13.794±0.00 6.064±0.65 3.003±0.00 14.784±8.23

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004LE CIL_0004LE_0001 CGP 5:119268692-119637199
CIL_0004B4 CIL_0004B4_0001 CGP 5:119452443-119637199

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001649 IDA osteoblast differentiation
GO:0003857 IDA 3-hydroxyacyl-CoA dehydrogenase activity
GO:0005102 IPI receptor binding
GO:0005777 IDA peroxisome
GO:0005778 IDA peroxisomal membrane
GO:0005782 TAS peroxisomal matrix
GO:0006635 IDA fatty acid beta-oxidation
GO:0006699 TAS bile acid biosynthetic process
GO:0008152 IDA:IEA metabolic process
GO:0008206 TAS bile acid metabolic process
GO:0008209 IDA androgen metabolic process
GO:0008210 IDA estrogen metabolic process
GO:0016020 IDA membrane
GO:0016491 IEA oxidoreductase activity
GO:0016508 IDA long-chain-enoyl-CoA hydratase activity
GO:0016853 IEA isomerase activity
GO:0033540 TAS fatty acid beta-oxidation using acyl-CoA oxidase
GO:0033559 TAS unsaturated fatty acid metabolic process
GO:0033989 TAS 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity
GO:0036109 TAS alpha-linolenic acid metabolic process
GO:0036111 IDA very long-chain fatty-acyl-CoA metabolic process
GO:0036112 IDA medium-chain fatty-acyl-CoA metabolic process
GO:0042803 IDA protein homodimerization activity
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0044594 IDA 17-beta-hydroxysteroid dehydrogenase (NAD+) activity
GO:0055114 IEA:IDA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000025385 Hsd17b4-001 protein_coding Mus_musculus 0 2180
ENSMUST00000139502 Hsd17b4-004 retained_intron Mus_musculus 0 357
ENSMUST00000127325 Hsd17b4-003 retained_intron Mus_musculus 0 252

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