C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ubiquitin protein ligase E3 component n-recognin 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000520539 UBR5-001 ENSG00000104517 9606 - 8:102253012-102412841 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartLiverOvaryTestisENST00000520539
Transcript ID Adipose Bladder Brain Breast Colon Heart Liver Ovary Testis
ENST00000520539 1.824±0.00 1.256±0.00 2.567±0.00 4.421±0.00 1.599±0.00 1.380±0.40 5.282±0.00 4.281±1.37 6.129±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00000S CIL_00000S_0001 CGP 8:102204502-102412841
CIL_00000U CIL_00000U_0001 CGP 8:102253012-102561017

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000209 IDA protein polyubiquitination
GO:0003723 IEA RNA binding
GO:0004842 TAS:IEA ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IBA cytoplasm
GO:0006281 IEA DNA repair
GO:0006511 TAS ubiquitin-dependent protein catabolic process
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0008270 IEA zinc ion binding
GO:0008283 TAS cell proliferation
GO:0016020 IDA membrane
GO:0016874 IEA ligase activity
GO:0033160 IMP positive regulation of protein import into nucleus, translocation
GO:0034450 IDA ubiquitin-ubiquitin ligase activity
GO:0035413 IMP positive regulation of catenin import into nucleus
GO:0042787 IBA protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043130 IEA ubiquitin binding
GO:0050847 IDA progesterone receptor signaling pathway
GO:0090263 IMP positive regulation of canonical Wnt signaling pathway
GO:1901315 IMP negative regulation of histone H2A K63-linked ubiquitination
GO:2000780 IMP negative regulation of double-strand break repair

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000110336 Ubr5-201 protein_coding Mus_musculus 0 12180

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