C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: maternal embryonic leucine zipper kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000536987 MELK-203 ENSG00000165304 9606 + 9:36572862-36677683 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderKidneyOvaryPlacentaENST00000536987
Transcript ID Bladder Kidney Ovary Placenta
ENST00000536987 0.122±0.00 0.038±0.00 0.525±0.00 0.537±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006K5 CIL_0006K5_0001 CGP 9:36336396-36677683
CIL_0006K6 CIL_0006K6_0001 CGP 9:36572862-37034185

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004715 IDA non-membrane spanning protein tyrosine kinase activity
GO:0005509 IDA calcium ion binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005886 IDA plasma membrane
GO:0005938 IDA cell cortex
GO:0006468 IEA protein phosphorylation
GO:0006915 IDA apoptotic process
GO:0008283 IDA cell proliferation
GO:0008289 IEA lipid binding
GO:0016020 IDA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030097 ISS hemopoiesis
GO:0043065 ISS positive regulation of apoptotic process
GO:0046777 IDA protein autophosphorylation
GO:0061351 ISS neural precursor cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000045607 Melk-001 protein_coding Mus_musculus 0 1408
ENSMUST00000137703 Melk-002 protein_coding Mus_musculus 0 612
ENSMUST00000137759 Melk-004 processed_transcript Mus_musculus 0 405
ENSMUST00000125708 Melk-003 protein_coding Mus_musculus 3e-36 158

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