C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000539276 ATP2A2-003 ENSG00000174437 9606 + 12:110281681-110347326 protein_coding

Homo sapiens EnsemblGRCh38

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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungOvaryPlacentaTestisENST00000539276
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENST00000539276 10.335±0.00 7.371±0.00 4.249±0.00 15.890±0.00 10.932±0.00 8.766±3.25 11.531±3.19 17.647±2.49 15.001±3.01 18.499±10.88 19.061±0.83 38.839±10.71

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001QG CIL_0001QG_0002 CGP 12:110124335-110351093
CIL_0001QF CIL_0001QF_0002 CGP 12:110280756-110403730

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0002026 IEA regulation of the force of heart contraction
GO:0005388 TAS:IEA calcium-transporting ATPase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005783 IEA endoplasmic reticulum
GO:0005789 IDA endoplasmic reticulum membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006810 TAS transport
GO:0006816 IEA calcium ion transport
GO:0006874 TAS cellular calcium ion homeostasis
GO:0006984 IEA ER-nucleus signaling pathway
GO:0007155 TAS cell adhesion
GO:0007596 TAS blood coagulation
GO:0008022 IPI protein C-terminus binding
GO:0008152 IEA metabolic process
GO:0008544 TAS epidermis development
GO:0010460 TAS positive regulation of heart rate
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0016529 IDA sarcoplasmic reticulum
GO:0019899 IPI enzyme binding
GO:0031095 TAS platelet dense tubular network membrane
GO:0033017 TAS sarcoplasmic reticulum membrane
GO:0034220 TAS ion transmembrane transport
GO:0043231 TAS intracellular membrane-bounded organelle
GO:0044548 IPI S100 protein binding
GO:0045822 IEA negative regulation of heart contraction
GO:0046872 IEA metal ion binding
GO:0055085 TAS transmembrane transport
GO:0055119 TAS relaxation of cardiac muscle
GO:0070296 TAS sarcoplasmic reticulum calcium ion transport
GO:0070588 IEA calcium ion transmembrane transport
GO:0086036 TAS regulation of cardiac muscle cell membrane potential
GO:0086039 TAS calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000031423 Atp2a2-201 protein_coding Mus_musculus 0 5234
ENSMUST00000177974 Atp2a2-202 protein_coding Mus_musculus 0 4028
ENSMUST00000179939 Atp2a2-203 protein_coding Mus_musculus 0 4028
ENSDART00000047201 atp2a2b-001 protein_coding Danio_rerio 0 1829

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