C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: numb homolog (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000557597 NUMB-003 ENSG00000133961 9606 - 14:73275216-73458522 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonKidneyLiverLungPlacentaTestisENST00000557597
Transcript ID Brain Breast Colon Kidney Liver Lung Placenta Testis
ENST00000557597 3.173±0.00 3.065±0.00 2.608±0.00 7.046±0.00 3.103±0.00 9.358±0.00 1.948±0.00 9.881±1.20

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008P0 CIL_0008P0_0001 VISTA 14:72878760-73482269
CIL_0001TR CIL_0001TR_0001 CGP 14:73237497-73463642

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0005925 IDA focal adhesion
GO:0007219 TAS Notch signaling pathway
GO:0007411 TAS axon guidance
GO:0021670 ISS lateral ventricle development
GO:0021849 ISS neuroblast division in subventricular zone
GO:0030136 IDA clathrin-coated vesicle
GO:0030335 IGI positive regulation of cell migration
GO:0050769 ISS positive regulation of neurogenesis
GO:1903077 IMP negative regulation of protein localization to plasma membrane

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000110298 Numb-007 nonsense_mediated_decay Mus_musculus 0 2784
ENSMUST00000154043 Numb-003 protein_coding Mus_musculus 0 2398
ENSMUST00000129335 Numb-002 protein_coding Mus_musculus 0 2121
ENSMUST00000085215 Numb-005 nonsense_mediated_decay Mus_musculus 0 1790
ENSMUST00000117217 Numb-001 protein_coding Mus_musculus 0 1583
ENSMUST00000021647 Numb-004 protein_coding Mus_musculus 0 1072
ENSMUST00000136848 Numb-009 protein_coding Mus_musculus 0 475
ENSMUST00000155112 Numb-006 protein_coding Mus_musculus 0 435
ENSMUST00000125089 Numb-011 retained_intron Mus_musculus 0 294
ENSMUST00000135962 Numb-008 protein_coding Mus_musculus 0 294
ENSMUST00000126943 Numb-010 protein_coding Mus_musculus 7.9874e-44 183

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