C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: insulin-like growth factor 1 receptor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000558762 IGF1R-002 ENSG00000140443 9606 + 15:98649044-98964529 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartLiverMuscleOvaryPlacentaTestisENST00000558762
Transcript ID Adrenal Brain Breast Colon Heart Liver Muscle Ovary Placenta Testis
ENST00000558762 1.657±0.00 1.940±0.00 0.793±0.00 1.695±0.00 0.677±0.19 1.519±1.30 1.338±0.00 1.398±0.11 1.663±1.35 2.544±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008TF CIL_0008TF_0001 VISTA 15:98414511-99018999
CIL_0009CO CIL_0009CO_0001 VISTA 15:98550452-99154111
CIL_0000GM CIL_0000GM_0001 CGP 15:98648971-99007795

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0006468 IEA protein phosphorylation
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0043548 IEA phosphatidylinositol 3-kinase binding
GO:0043560 IEA insulin receptor substrate binding
GO:0046777 IEA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000005671 Igf1r-201 protein_coding Mus_musculus 0 5467
ENSDART00000046542 igf1rb-001 protein_coding Danio_rerio 0 787
ENSDART00000010189 igf1ra-001 protein_coding Danio_rerio 1e-36 161
ENSDART00000135649 igf1ra-002 processed_transcript Danio_rerio 1e-26 128

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