C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: WW domain containing oxidoreductase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000566780 WWOX-005 ENSG00000186153 9606 + 16:78099413-79212667 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainColonHeartKidneyLungOvaryPlacentaTestisENST00000566780
Transcript ID Adipose Brain Colon Heart Kidney Lung Ovary Placenta Testis
ENST00000566780 0.780±0.00 3.952±0.00 0.588±0.00 0.536±0.00 2.133±0.00 1.020±0.00 2.656±1.46 0.878±0.10 3.231±0.39

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008I7 CIL_0008I7_0001 VISTA 16:77875854-78477465
CIL_0003OH CIL_0003OH_0001 CGP 16:78022515-79212667
CIL_0007SZ CIL_0007SZ_0001 VISTA 16:78053124-78654788
CIL_00085A CIL_00085A_0001 VISTA 16:78063958-78665023
CIL_0001PE CIL_0001PE_0001 CGP 16:78099413-79600714

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001649 IEA osteoblast differentiation
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 TAS cytoplasm
GO:0005739 ISS mitochondrion
GO:0005794 IDA Golgi apparatus
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0005902 IDA microvillus
GO:0008152 IEA metabolic process
GO:0008202 TAS steroid metabolic process
GO:0016055 IEA Wnt signaling pathway
GO:0016491 TAS:IEA oxidoreductase activity
GO:0019899 IPI enzyme binding
GO:0030178 IDA negative regulation of Wnt signaling pathway
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046983 TAS protein dimerization activity
GO:0048037 TAS cofactor binding
GO:0048705 ISS skeletal system morphogenesis
GO:0050662 TAS coenzyme binding
GO:0055114 TAS oxidation-reduction process
GO:0071560 IDA cellular response to transforming growth factor beta stimulus
GO:0072332 IEA intrinsic apoptotic signaling pathway by p53 class mediator
GO:0097191 IEA extrinsic apoptotic signaling pathway
GO:2001238 ISS positive regulation of extrinsic apoptotic signaling pathway
GO:2001241 IEA positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000004756 Wwox-001 protein_coding Mus_musculus 0 1341
ENSMUST00000109108 Wwox-004 protein_coding Mus_musculus 0 1177
ENSMUST00000160862 Wwox-003 protein_coding Mus_musculus 0 1177
ENSMUST00000160005 Wwox-005 processed_transcript Mus_musculus 0 508
ENSMUST00000109107 Wwox-002 protein_coding Mus_musculus 0 508

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