C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: LIM and SH3 protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000002834 LASP1 9606 + 17:38869859-38921770 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000318008 LASP1-001 38869859-38921770 protein_coding
  ENST00000419929 LASP1-002 38873890-38915141 protein_coding
  ENST00000433206 LASP1-201 38869859-38921769 protein_coding
  ENST00000435347 LASP1-202 38870143-38921761 protein_coding
  ENST00000443937 LASP1-005 38870061-38919175 nonsense_mediated_decay
  ENST00000579123 LASP1-008 38914397-38916837 protein_coding
  ENST00000581485 LASP1-009 38890234-38915129 retained_intron
  ENST00000584106 LASP1-004 38870061-38899200 retained_intron
  ENST00000585841 LASP1-003 38870031-38919326 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000318008ENST00000419929ENST00000433206ENST00000435347ENST00000443937ENST00000584106
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000318008 14.304±0.00 47.946±0.00 2.033±0.00 15.104±11.75 19.065±10.34 9.404±0.00 3.111±1.49 6.797±5.30 6.090±2.51 11.362±9.10 2.976±1.84 45.837±23.75 49.615±8.56 18.142±14.18
ENST00000419929 N/A N/A 2.350±0.00 4.795±0.00 N/A N/A N/A N/A 5.326±0.00 N/A N/A 10.016±0.00 N/A 24.718±0.00
ENST00000433206 12.673±0.00 18.800±0.00 N/A N/A N/A 7.223±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000435347 N/A N/A 1.093±0.00 2.006±0.00 N/A 2.152±0.00 0.503±0.00 3.795±0.00 1.888±0.00 4.100±0.00 0.230±0.00 16.823±8.32 15.880±4.29 2.083±0.00
ENST00000443937 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 21.414±0.00 N/A
ENST00000584106 N/A N/A 1.928±0.00 N/A N/A N/A N/A N/A N/A 3.602±0.00 2.433±0.00 64.023±0.00 35.822±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006QO CIL_0006QO_0001 CGP 17:38847865-38921770

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005070 TAS SH3/SH2 adaptor activity
GO:0005515 IPI:IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005925 IDA focal adhesion
GO:0006811 ISS ion transport
GO:0008270 IEA zinc ion binding
GO:0009967 TAS positive regulation of signal transduction
GO:0015075 ISS ion transmembrane transporter activity
GO:0030864 ISS cortical actin cytoskeleton
GO:0034220 IEA ion transmembrane transport
GO:0051015 IEA actin filament binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057867 lasp1 LIM and SH3 protein 1 protein_coding Danio_rerio
ENSMUSG00000038366 Lasp1 LIM and SH3 protein 1 protein_coding Mus_musculus

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