C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CDC-like kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000013441 CLK1 9606 - 2:200853009-200864744 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000321356 CLK1-001 200853009-200864699 protein_coding
  ENST00000409403 CLK1-006 200853113-200864662 nonsense_mediated_decay
  ENST00000409769 CLK1-005 200853098-200858166 protein_coding
  ENST00000432425 CLK1-003 200853081-200864656 nonsense_mediated_decay
  ENST00000434813 CLK1-007 200853196-200864561 protein_coding
  ENST00000461326 CLK1-013 200853247-200854134 retained_intron
  ENST00000461981 CLK1-002 200853076-200860983 retained_intron
  ENST00000464454 CLK1-016 200853077-200854013 retained_intron
  ENST00000472679 CLK1-015 200853082-200853995 retained_intron
  ENST00000473565 CLK1-004 200853081-200864691 retained_intron
  ENST00000481641 CLK1-012 200861090-200864252 retained_intron
  ENST00000482590 CLK1-010 200861332-200864658 retained_intron
  ENST00000492793 CLK1-011 200860965-200864657 processed_transcript
  ENST00000496205 CLK1-014 200853332-200854886 retained_intron
  ENST00000621181 CLK1-201 200853009-200864744 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000321356ENST00000409403ENST00000409769ENST00000432425ENST00000434813ENST00000461981ENST00000473565
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000321356 N/A N/A 2.743±0.00 7.954±0.00 16.083±0.00 4.690±0.00 2.979±0.00 N/A N/A N/A 3.340±0.00 16.668±6.33 5.795±2.67 12.317±0.00
ENST00000409403 N/A N/A N/A N/A 4.487±0.00 12.630±0.00 N/A N/A 1.733±0.00 28.502±0.00 10.253±0.00 11.335±0.00 5.152±0.00 16.959±2.73
ENST00000409769 N/A N/A N/A N/A N/A N/A N/A 6.667±0.00 N/A N/A N/A N/A N/A N/A
ENST00000432425 6.600±0.00 N/A N/A 3.138±0.00 7.416±0.00 7.690±0.00 N/A 5.332±0.00 2.358±0.00 N/A N/A 9.815±3.17 3.543±0.17 10.460±0.00
ENST00000434813 4.482±0.00 12.691±0.00 N/A 4.098±0.00 5.477±0.00 19.224±0.00 9.300±0.00 8.762±0.00 2.852±0.00 49.636±0.00 19.652±0.00 N/A N/A 10.415±3.39
ENST00000461981 N/A 7.261±0.00 N/A 1.636±0.00 4.820±0.96 N/A N/A 2.875±0.65 N/A N/A N/A 3.618±1.33 N/A N/A
ENST00000473565 2.315±0.00 7.121±0.00 7.229±0.00 8.255±5.51 8.167±0.00 10.927±0.00 4.518±0.34 7.352±2.03 6.740±0.00 21.710±0.00 4.192±0.00 6.591±1.93 1.719±0.22 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002AX CIL_0002AX_0001 CGP 2:200810594-200864744
CIL_0002AY CIL_0002AY_0001 CGP 2:200853009-200889303

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004712 IEA protein serine/threonine/tyrosine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004715 TAS non-membrane spanning protein tyrosine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006468 IEA protein phosphorylation
GO:0008283 TAS cell proliferation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0018107 IEA peptidyl-threonine phosphorylation
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0043484 IMP regulation of RNA splicing
GO:0046777 IEA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005908 clk4b CDC-like kinase 4b protein_coding Danio_rerio
ENSDARG00000089372 clk4a CDC-like kinase 4a protein_coding Danio_rerio
ENSMUSG00000026034 Clk1 CDC-like kinase 1 protein_coding Mus_musculus

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