C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CDC-like kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026034 Clk1 10090 - 1:58410189-58424066 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034868 Clk1-001 58412000-58424066 protein_coding
  ENSMUST00000123580 Clk1-006 58412000-58416765 retained_intron
  ENSMUST00000129303 Clk1-009 58412316-58413825 processed_transcript
  ENSMUST00000129577 Clk1-003 58416143-58424066 retained_intron
  ENSMUST00000131051 Clk1-012 58416910-58417426 retained_intron
  ENSMUST00000135380 Clk1-008 58414615-58421258 retained_intron
  ENSMUST00000139787 Clk1-011 58412000-58412861 processed_transcript
  ENSMUST00000141570 Clk1-010 58412000-58413437 processed_transcript
  ENSMUST00000147258 Clk1-007 58421626-58424066 retained_intron
  ENSMUST00000148330 Clk1-004 58412000-58424066 nonsense_mediated_decay
  ENSMUST00000151338 Clk1-005 58412000-58424066 nonsense_mediated_decay
  ENSMUST00000156931 Clk1-002 58410189-58424066 retained_intron
  ENSMUST00000186552 Clk1-013 58414590-58420398 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034868ENSMUST00000123580ENSMUST00000129577ENSMUST00000147258ENSMUST00000148330ENSMUST00000151338ENSMUST00000186552
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034868 10.212±2.30 3.739±1.33 54.530±20.61 19.559±3.88 8.402±1.96 7.251±1.24 6.186±1.16 7.836±3.26 21.893±14.96 17.832±5.94 7.767±2.28 21.205±18.85 28.930±4.75 2.927±0.66
ENSMUST00000123580 14.881±6.10 9.581±1.07 N/A 15.278±3.17 15.211±4.13 10.639±2.74 5.366±0.49 6.848±1.03 8.158±4.78 18.761±0.90 N/A 14.016±3.11 13.068±0.00 3.020±0.19
ENSMUST00000129577 6.680±0.62 4.330±0.83 26.920±14.02 10.635±7.51 9.289±2.71 7.104±0.85 4.799±0.00 4.993±1.25 9.919±6.38 13.008±3.68 2.715±0.00 10.835±5.85 5.927±1.07 2.567±0.35
ENSMUST00000147258 N/A N/A N/A 159.299±0.00 N/A N/A N/A N/A N/A N/A N/A 705.448±0.00 266.632±5.13 98.256±0.00
ENSMUST00000148330 9.937±0.44 N/A 51.186±14.58 26.177±9.53 12.773±3.76 6.585±2.31 7.717±2.94 6.198±1.68 13.288±6.66 12.040±0.00 7.585±1.18 25.681±18.35 12.578±0.22 8.085±1.02
ENSMUST00000151338 N/A N/A N/A 13.275±0.00 23.412±0.00 N/A N/A N/A 6.000±2.63 12.294±0.00 N/A 8.856±2.71 N/A 5.660±0.00
ENSMUST00000186552 N/A 8.644±1.22 N/A 51.388±0.00 N/A N/A N/A N/A N/A N/A N/A 144.163±60.29 63.661±22.51 23.084±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002AX CIL_0002AX_0002 CGP 1:58392898-58424066
CIL_0002AY CIL_0002AY_0002 CGP 1:58410189-58445486

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004712 IEA protein serine/threonine/tyrosine kinase activity
GO:0004713 IDA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0018107 IDA peptidyl-threonine phosphorylation
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0043484 IEA regulation of RNA splicing
GO:0046777 IDA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005908 clk4b CDC-like kinase 4b protein_coding Danio_rerio
ENSDARG00000089372 clk4a CDC-like kinase 4a protein_coding Danio_rerio
ENSG00000013441 CLK1 CDC-like kinase 1 protein_coding Homo_sapiens

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