C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neurexin 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000021645 NRXN3 9606 + 14:78242391-79868290 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000281127 NRXN3-005 79279413-79868290 protein_coding
  ENST00000335750 NRXN3-201 78614932-78988299 protein_coding
  ENST00000428277 NRXN3-006 79279906-79864417 protein_coding
  ENST00000553363 NRXN3-010 78278643-78651311 protein_coding
  ENST00000553631 NRXN3-009 78403731-78709507 protein_coding
  ENST00000553803 NRXN3-014 79298795-79573011 processed_transcript
  ENST00000554719 NRXN3-001 78403750-79862443 protein_coding
  ENST00000554738 NRXN3-002 78242391-79862033 nonsense_mediated_decay
  ENST00000555073 NRXN3-012 79280502-79663892 processed_transcript
  ENST00000555387 NRXN3-007 79280263-79862454 nonsense_mediated_decay
  ENST00000556003 NRXN3-013 79314051-79861959 processed_transcript
  ENST00000556088 NRXN3-008 78243602-78645427 retained_intron
  ENST00000556496 NRXN3-003 78614932-78988299 retained_intron
  ENST00000557081 NRXN3-011 78698220-78709641 protein_coding
  ENST00000557594 NRXN3-004 79279339-79862478 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000281127ENST00000428277ENST00000554738ENST00000555387ENST00000557594
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000281127 N/A N/A N/A 1.103±0.00 N/A 0.238±0.00 N/A N/A 0.463±0.00 N/A N/A N/A N/A N/A
ENST00000428277 0.227±0.00 0.608±0.00 0.390±0.00 7.681±2.38 0.935±0.63 3.951±3.31 0.112±0.09 0.563±0.00 0.555±0.55 1.275±0.51 0.027±0.02 0.288±0.11 0.514±0.34 1.127±0.00
ENST00000554738 N/A N/A N/A 3.215±0.28 0.515±0.00 N/A N/A N/A N/A N/A N/A 0.042±0.00 N/A N/A
ENST00000555387 N/A N/A 0.204±0.00 N/A N/A N/A 0.071±0.00 N/A N/A 1.047±0.00 N/A N/A N/A N/A
ENST00000557594 N/A N/A N/A N/A 2.010±0.00 2.567±0.69 0.155±0.07 0.302±0.00 1.704±1.69 1.284±0.00 N/A 0.206±0.05 0.572±0.47 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004U1 CIL_0004U1_0001 CGP 14:77800083-79868290
CIL_0008FT CIL_0008FT_0001 VISTA 14:78139980-78740994
CIL_0004U0 CIL_0004U0_0001 CGP 14:78242391-80387757

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 ISS angiogenesis
GO:0004872 TAS receptor activity
GO:0005246 IEA calcium channel regulator activity
GO:0005515 IEA protein binding
GO:0005887 TAS integral component of plasma membrane
GO:0007158 TAS neuron cell-cell adhesion
GO:0007268 IEA synaptic transmission
GO:0007269 IEA neurotransmitter secretion
GO:0007411 TAS axon guidance
GO:0007416 IEA synapse assembly
GO:0007612 IGI learning
GO:0016021 IEA integral component of membrane
GO:0030534 IGI adult behavior
GO:0035176 IGI social behavior
GO:0046872 IEA metal ion binding
GO:0050839 TAS cell adhesion molecule binding
GO:0051965 IEA positive regulation of synapse assembly
GO:0071625 IGI vocalization behavior
GO:0090129 IEA positive regulation of synapse maturation
GO:0097109 TAS neuroligin family protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043746 nrxn3a neurexin 3a protein_coding Danio_rerio
ENSDARG00000062693 nrxn3b neurexin 3b protein_coding Danio_rerio
ENSMUSG00000066392 Nrxn3 neurexin III protein_coding Mus_musculus

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